AI Article Synopsis

  • * The study analyzes the clinical features, diagnosis, treatment, and prognosis of DLBCL associated with MTX therapy, aiming to enhance awareness among healthcare professionals about this condition.
  • * Findings from this case provide new insights that could aid in the clinical diagnosis and management of DLBCL linked to methotrexate in similar patients.

Article Abstract

A case of primary oral mucosal diffuse large B-cell lymphoma(DLBCL)due to long-term use of methotrexate(MTX)for the treatment of rheumatoid arthritis(RA)was admitted to the Department of Hematology,Fujian Medical University Union Hospital.We analyzed and discussed the clinical features,diagnosis and treatment,and prognosis of specific malignant lymphoma induced by MTX in this RA patient.Our purpose is to improve the awareness and knowledge of other iatrogenic immunodeficiency-associated lymphoproliferative disorders of clinicians and pathologists.This study provides a new reference for the clinical diagnosis and treatment of MTX-associated DLBCL.

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http://dx.doi.org/10.3881/j.issn.1000-503X.13717DOI Listing

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