Case: Here, we present the case of a pediatric polytrauma patient found to have lower extremity intra-arterial fat embolism causing ischemic necrosis and ultimately necessitating below-the-knee amputation.
Conclusion: Fat embolism, a common complication of long bone fractures in adults, can be associated with significant morbidity. Although rare, it should be considered among the possible etiologies for a pulseless limb after trauma. Early fracture stabilization may prevent fat embolism and fat embolism syndrome; however, there is no known definitive treatment, and management is supportive.
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http://dx.doi.org/10.2106/JBJS.CC.20.00485 | DOI Listing |
Intern Med
December 2024
Department of Cardiovascular Medicine, Kyoto University Hospital, Japan.
A 74-year-old woman presented with sudden dyspnea 22 h after orthopedic surgery. Echocardiography revealed significant right ventricular dilatation, suggesting the development of acute pulmonary embolism. However, contrast computed tomography showed no signs of pulmonary thromboembolism, leading to suspicion of fat embolism syndrome (FES).
View Article and Find Full Text PDFJ Belg Soc Radiol
December 2024
Radiology Department, UCL Bruxelles, Cliniques Universitaires Saint-Luc, Belgium Avenue Hippocrate 10, 1200 Bruxelles, Belgium.
Spectral tomography offers valuable complementary diagnostic tools in the setting of cerebral fat macroembolism, a rare condition often presenting with nonspecific clinical symptoms.
View Article and Find Full Text PDFJ Mater Chem B
December 2024
Department of Burns, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China.
Acute lung injury (ALI) is a critical clinical disease caused by direct factors (inhalation injury, gastroesophageal reflux, ) or indirect factors (including infection, sepsis, burn, shock, trauma, acute pancreatitis, fat embolism, drug overdose, ). ALI is characterized mainly by diffuse interstitial and alveolar edema caused by an uncontrolled inflammatory response and damage to the alveoli-capillary barrier and has very high morbidity and mortality rates. Currently, there is no effective treatment strategy other than mechanical ventilation, fluid management or other supportive treatments.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
December 2024
Department of Orthopedics and Rehabilitation, University of Iowa, Iowa City, IA, United States.
Duchenne muscular dystrophy (DMD) is a progressive, fatal muscle wasting disease caused by X-linked mutations in the dystrophin gene. Alongside the characteristic muscle weakness, patients face a myriad of skeletal complications, including osteoporosis/osteopenia, high susceptibility to vertebral and long bone fractures, fat embolism post-fracture, scoliosis, and growth retardation. Those skeletal abnormalities significantly compromise quality of life and are sometimes life-threatening.
View Article and Find Full Text PDFInt J Surg Case Rep
November 2024
Department of Public Health, School of Medicine, Universitas Ciputra, Surabaya, Indonesia.
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