Purpose: Compliant mechanisms are commonly used in the design of manipulator and surgical robotic tools for minimally invasive surgery (MIS) thanks to their compactness, ability of miniaturization and lower part count. However, conventional compliant joint has higher internal stiffness, which limits the bending radius. To overcome this problem, a novel tendon-driven manipulator structure based on monolithic compliant rolling-contact joint (CRCJ) is proposed.
Methods: The proposed rolling-contact mechanism is used to prevent cable slack during actuation, which occurs in conventional compliant joint design. By means of selective laser sintering (SLS) technique, the CRCJ can be fabricated in a monolithic structure, thus granting the CRCJ both the advantages of compliant joints and rolling-contact mechanism. Simulations with nonlinear finite element analysis (FEA) and experiments were conducted to evaluate and compare the mechanical properties of the proposed CRCJ with conventional leaf-type compliant joint including the bending and compliant motion.
Results: Experimental results showed that the CRCJ has lower bending stiffness, higher maximum bending angle (over [Formula: see text]) and a higher compliance compared to conventional compliant hinges, which allows a larger workspace and reduces the possibility of tissue injury. Agreement was also found between the nonlinear FEA and experiments regarding the relation between actuation force and bending angle. A primary prototype of a 3-DOF handheld laparoscopic manipulator with a diameter of 7 mm was further developed.
Conclusion: A dexterous tendon-driven monolithic manipulator structure based on CRCJ for MIS is proposed. A preliminary prototype of a handheld laparoscopic manipulator demonstrates the capability of the CRCJ for steerable medical devices. However, design improvements based on FEA and application-orientated prototypes considering anatomical requirements still show room for improvements.
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http://dx.doi.org/10.1007/s11548-021-02442-w | DOI Listing |
J Exp Bot
December 2024
Centre of Plant Structural and Functional Genomics, Institute of Experimental Botany, Czech Acad Sci, Šlechtitelů 31, Olomouc 77900, Czech Republic.
Cytosine (DNA) methylation plays important roles in silencing transposable elements, plant development, genomic imprinting, stress responses, and maintenance of genome stability. To better understand the functions of this epigenetic modification, several tools have been developed to manipulate DNA methylation levels. These include mutants of DNA methylation writers and readers, targeted manipulation of locus-specific methylation, and the use of chemical inhibitors.
View Article and Find Full Text PDFInorg Chem
December 2024
Institute of Nano Science and Technology, Sector-81, Mohali, Punjab 140306, India.
Among lanthanide-based single-molecule magnets (SMMs), erbium(III) is a Kramers ion, apart from dysprosium(III), which provides magnetic bistability in the presence of a suitable coordination environment. However, Er-based SMMs exhibit significantly less magnetic anisotropy than Dy because their prolate electronic density necessitates equatorially correlated ligands to minimize the charge contact with the Er atom. Here, in this work, we have computationally investigated the heteroleptic organometallic complexes with an Er(III) atom sandwiched between two distinct cyclic rings (five- and eight-membered) with the aim of tuning the magnetic anisotropy via exploiting the ligand field.
View Article and Find Full Text PDFLangenbecks Arch Surg
December 2024
Department of Surgical Oncology, Nagasaki University Graduate School of Biomedical Science, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Background: Lateral pelvic lymph node dissection (LPND) is a challenging surgical technique with complex anatomy and narrow pelvic manipulation. The outcomes of robotic and laparoscopic surgery for LPND are still unclear.
Methods: We retrospectively reviewed 169 consecutive patients who underwent rectal cancer surgery with LPND between 2016 and 2023.
Sports (Basel)
November 2024
Sport, Performance, and Nutrition Research Group, School of Allied Health, Human Services and Sport, La Trobe University, 1 Kingsbury Drive, Bundoora, Melbourne, VIC 3083, Australia.
The purpose of this study was to explore the experiential knowledge of tennis coaches as it related to the development of grip positions in tennis athletes. Accredited tennis coaches (n = 11) completed semi-structured interviews consisting of open-ended questions about their coaching background, the importance of grip positions compared with other areas of foundational development, and their opinions on using physically-constraining tools (PCTs). Two major themes, "Grip positions are an adaptive skill" and "Why and how do I modify an athlete's grip?", were identified.
View Article and Find Full Text PDFNanomaterials (Basel)
December 2024
Department of Energy and Materials Engineering, Dongguk University, Seoul 04620, Republic of Korea.
Nanomaterial properties such as size, structure, and composition can be controlled by manipulating radiation, such as gamma rays, X-rays, and electron beams. This control allows scientists to create materials with desired properties that can be used in a wide range of applications, from electronics to medicine. This use of radiation for nanotechnology is revolutionizing the way we design and manufacture materials.
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