AI Article Synopsis
- The study aimed to establish normal reference ranges for the fetal left ventricular Modified Myocardial Performance Index (Mod-MPI) and assess the agreement between manual and automatic measurements.
- The research involved a multicentre, cross-sectional design that analyzed 2081 fetuses across various stages of pregnancy using standardized ultrasound methods.
- The results showed a correlation between gestational age and Mod-MPI values, indicating valid reference values that support the use of automated measurements for efficiency in clinical practice.
Article Abstract
Objectives: The primary aim of this study was to establish the normal reference ranges of the fetal left ventricular (LV) Modified Myocardial Performance Index (Mod-MPI). A secondary aim was to evaluate the agreement between manual and automatic measurements for fetal Mod-MPI.
Design: A prospective, multicentre, cross-sectional study.
Participants: Normal singleton pregnancies.
Methods: The LV functions of normal singleton pregnancies were assessed in nine centres covering eight provinces in China using unified ultrasound protocols and settings and standardised measurements by pulsed Doppler at 20-24, 28-32 and 34-38 weeks of gestation. The isovolumetric relaxation time (IRT), isovolumetric contraction time, ejection time (ET) and Mod-MPI were measured both automatically and manually.
Results: This cross-sectional study included 2081 fetuses, and there was a linear correlation between gestational age (GA) and Mod-MPI (0.416+0.001×GA (weeks), p<0.001, r=0.013), IRT (36.201+0.162× GA (weeks), p<0.001, r=0.021) and ET (171.418-0.078*GA (weeks), p<0.001, r=0.002). This finding was verified using longitudinal data in a subgroup of 610 women. The agreement between the manual and automated measurements for Mod-MPI was good.
Conclusions: We constructed normal reference values of fetal LV Mod-MPI. Automatic measurement can be considered for ease of measurement in view of the good agreement between the automatic and manual values.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264880 | PMC |
| http://dx.doi.org/10.1136/bmjopen-2021-049640 | DOI Listing |
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