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Noninvasive Assessment of Vascular Function: From Physiological Tests to Biomarkers.
JACC Asia
December 2024
Department of Regenerative Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Vascular function is impaired by conditions such as hypertension, dyslipidemia, and diabetes as well as coronary risk factors including age, smoking, obesity, menopause and physical inactivity. Measurement of vascular function is useful not only for assessment of atherosclerosis itself but also in many other aspects such as understanding the pathophysiology, assessing treatment efficacy, and predicting prognosis of cardiovascular events. It is therefore important to accurately assess the extent of vascular function.
View Article and Find Full Text PDFPrimary Cardiac Myxofibrosarcoma of the Left Atrium with Heterologous Elements Mimicking a Cardiac Myxoma.
Am J Case Rep
January 2025
Department of Anatomic Pathology and Cytopathology, University Hospital "Dr. José Eleuterio González", Monterrey, Mexico.
BACKGROUND Primary cardiac malignancies are extremely rare, with an incidence of 0.07% on autopsy series. Primary sarcomas represent up to 95% of malignant neoplasms, with myxofibrosarcomas accounting for only 10%.
View Article and Find Full Text PDFA multimodal neuroimaging study of cerebrovascular regulation: protocols and insights of combining electroencephalography, functional near-infrared spectroscopy, transcranial Doppler ultrasound, and physiological parameters.
J Neural Eng
January 2025
Cerebrovascular Concussion Lab, Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada.
. The current paper describes the creation of a simultaneous trimodal neuroimaging protocol. The authors detail their methodological design for a subsequent large-scale study, demonstrate the ability to obtain the expected physiologically induced responses across cerebrovascular domains, and describe the pitfalls experienced when developing this approach.
View Article and Find Full Text PDFTracking autonomic nervous system activity using surface ECG: Personalized, multiparametric evaluation.
J Electrocardiol
January 2025
Division of Cardiovascular Medicine, The University of Iowa, Iowa City, IA, United States of America.
Article Synopsis
- This review discusses the noninvasive evaluation of cardiac autonomic nervous system activity (ANSA) through easily accessible parameters like heart rate (HR) and heart-rate variability (HRV), highlighting their importance in risk assessment for sudden cardiac death.
- The translation of these parameters from controlled lab settings to real-world ambulatory environments faces challenges due to various uncontrolled factors such as blood pressure changes and physical activity.
- To improve the accuracy of ANSA evaluations in everyday settings, the authors suggest using a multi-sensor and multiparametric approach, along with data fusion and machine-learning techniques.
Pearls and Pitfalls of T1-Weighted Neuroimaging: A Primer for the Clinical Radiologist.
Acad Radiol
November 2024
Department of Radiology, Los Angeles General Medical Center, Los Angeles, California, USA (A.L., S.Z., P.R., D.C.P., M.S.S., R.A.).
All T1-weighted images are built upon one of two fundamental pulse sequences, spin-echo and gradient echo, each of which has distinct signal characteristics and clinical applications. Moreover, within each broadly defined category of T1-weighting, acquisition parameters can be modified to affect image quality, contrast, and scan duration; each tailored sequence has unique advantages, drawbacks, clinical indications, and potential artifacts. In this review, we describe key features that distinguish different types of T1-weighted sequences and discuss the utility of each sequence for specific clinical settings, including neuro-oncology, vasculopathy, and pediatric neuroradiology.
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