The neurotropic effects of pyroglutamyl-seryl-phenylalanine amide, the thyrotropin-releasing hormone analog, have been studied in experiments on male rats. Electrodes were implanted in the hippocamp and the optic cortex for registration of electroencephalograms. The analog administered intraperitoneally decreased the time of onset of slow sleep increasing the duration of this phase. The effects of the analog increased with an increase in a dose of the agent.
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