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Comparison of transcutaneous bilirubin under patch-covered skin with total serum bilirubin in neonates undergoing phototherapy.
J Trop Pediatr
December 2024
Department of Neonatology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand 249203, India.
Transcutaneous bilirubinometry (TcB) is a recognized tool to monitor neonatal hyperbilirubinemia, demonstrating a high correlation with total serum bilirubin (TSB) before phototherapy. However, once phototherapy is started, TcB may become unreliable. To evaluate the correlation and agreement of TcB measured under variously patched skin at different sites (a coin over the sternum, eye shield over the forehead, and diaper area at the back) with TSB.
View Article and Find Full Text PDFGreen solid lipid nanoparticles by coacervation of fatty acids: An innovative cosmetic ingredient for the delivery of anti-age compounds through the skin.
Int J Pharm
January 2025
University of Turin, Department of Drug Science and Technology, via Pietro Giuria 9, 10125 Turin, Italy; University of Turin, Department of Medical Sciences, Dermatologic Clinic, Via Cherasco 23, 10126 Turin, Italy.
The constant exposure of the skin to internal and external stimuli drives towards skin aging and lost in skin hydration and elasticity. Chronic low-grade inflammation, called inflammaging, and oxidative stress are the leading causes of this phenomenon. Fatty acid coacervation is a preparation method for Solid Lipid Nanoparticles (SLNs), which does not employ solvents, and is associated to low energy consumption.
View Article and Find Full Text PDFOptical coherence tomography-enabled classification of the human venoatrial junction.
J Biomed Opt
January 2025
Columbia University, Department of Electrical Engineering, New York, United States.
Significance: Radiofrequency ablation to treat atrial fibrillation (AF) involves isolating the pulmonary vein from the left atria to prevent AF from occurring. However, creating ablation lesions within the pulmonary veins can cause adverse complications.
Aim: We propose automated classification algorithms to classify optical coherence tomography (OCT) volumes of human venoatrial junctions.
Severe Allergic Contact Dermatitis to Hair Dye in a Patient With Atopic Dermatitis During Dupilumab Therapy.
Contact Dermatitis
January 2025
Dermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Calretinin-expressing neurons in the basal forebrain specifically contact granule cells in the olfactory bulb and modulate odor learning.
J Neurosci
January 2025
Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada, K1N 6N5
GABAergic neurons in basal forebrain (BF) nuclei project densely to all layers of the mouse main olfactory bulb (OB), the first relay in odor information processing. However, BF projection neurons are diverse and the contribution of each subtype to odor information processing is not known. In the present study, we used retrograde and anterograde tracing methods together with whole-brain light-sheet analyses, patch-clamp recordings coupled with optogenetic and chemogenetic approaches during spontaneous odor discrimination, and go/no-go odor discrimination/learning tests to characterize the synaptic targets in the OB of BF calretinin-expressing (CR+) GABAergic cells and to reveal their functional implications.
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