We report a case of spontaneous pneumomediastinum, pneumothorax, emphysema subcutaneous and pneumorrhachis, occurring in an adolescent resulting positive to SARS-CoV-2 nasopharyngeal swab. At the admission in Emergency Department, the child presented with left cervical and sternal pain, without respiratory symptoms. Radiological studies showed sizeable pneumomediastinum, bilateral apical pneumothorax, massive emphysema subcutaneous and pneumorrhachis. Patients' clinical conditions stood stable during the monitoring and he only needed conservative management. To our knowledge, this is the first description of spontaneous pneumomediastinum, pneumothorax, emphysema subcutaneous and pneumorrhachis, in a COVID-19 adolescent without concomitant pneumonia.
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http://dx.doi.org/10.26355/eurrev_202106_26152 | DOI Listing |
Brain Spine
December 2024
Department of Neurosurgery, Neuroscience Center, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
Research Question: to describe and investigate the case of an 11-year-old boy with the concomitant pneumocephalus, subcutaneous- and orbitopalpebral emphysema after the removal of a giant meningioma. Furthermore, our aim is to discuss the findings and the pathophysiology in relation to cases found in literature.
Material And Methods: We performed a search in PubMed, Cochrane, MEDLINE and Google Scholar by the usage of the words orbital or periorbital, combined with emphysema and neurosurgery.
Cureus
December 2024
Pediatric Anesthesiology, University of Arkansas for Medical Sciences, Little Rock, USA.
Subcutaneous emphysema results from air or gas being forced into the fascial spaces of subcutaneous tissue. Once the air or gas has entered the fascial spaces, it travels along connective tissue causing a mass effect and swelling. This rare complication usually presents with mild severity during the immediate postoperative period following surgical procedures of the head or neck regions and self-resolves with conservative treatment.
View Article and Find Full Text PDFRev Physiol Biochem Pharmacol
January 2025
Institute of Medical Sciences, University of Aberdeen, Aberdeen, Scotland, UK.
Ribosomes use multiple electrical forces to regulate new protein construction, to ensure efficient protein cotranslation, chaperoning, and folding. When these electrical regulatory forces are disrupted as in point charge mutations, specific disease occurs from aberrantly folded proteins. α1 antitrypsin deficiency is perhaps the best-known misfolded protein disease and is covered in some detail.
View Article and Find Full Text PDFCureus
December 2024
Critical Care Medicine, Coordinación de Terapia Intensiva y Hemodinamia de Hospitales de 2º Nivel Instituto Mexicano del Seguro Social Bienestar, Mexico City, MEX.
Hamman's syndrome is characterized by spontaneous pneumomediastinum triggered by Valsalva maneuvers and is an uncommon complication during labor and the postpartum period. It is typically benign and managed conservatively with oxygen therapy and analgesia. We present the clinical case of a 21-year-old primigravida who developed spontaneous pneumomediastinum during labor, manifesting with subcutaneous emphysema and dyspnea.
View Article and Find Full Text PDFJ Oral Maxillofac Surg
January 2025
Research Assistant, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Ondokuz Mayıs University, Samsun, Turkey. Electronic address:
Background: Arthrocentesis is a minimally invasive procedure for treating intra-articular temporomandibular disorders. While it is considered relatively safe, like any surgical intervention, it carries potential risks.
Purpose: The study purpose was to estimate the frequency of complications associated with temporomandibular joint arthrocentesis, identify risk factors, and improve preparedness for effective prevention and management strategies.
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