Semiotic Thoughts on Biological Sequence Representations.

The deluge of biological sequences ranging from those of proteins, DNA and RNA to genomes has motivated to devise models to represent them, which are further used to contrast those sequences. Here we present a brief bibliometric description of the research area devoted to the representation of biological sequences and highlight the semiotic elements of this process. Finally, we argue that this research area must learn from the evolution of mathematical chemistry and try to avoid its pitfalls.