Traffic incidents occurring on the road interrupt the smooth mobility of traffic flow and lead to traffic congestion. Although there has been a proliferation of studies that attempt to estimate the spatiotemporal impact of a traffic incident, most, if not all, of them focus exclusively on the differentiation of bi-level traffic status. In this research, we propose to incorporate multiple congestion levels in the spatiotemporal analysis for the impact of a traffic incident, which is new to the literature. The input to our model includes the historical speed on a given road and the occurrence time and location of the incident. The model then outputs the spatiotemporal impact region with multiple congestion levels. We first use a discriminant indicator to initially indicate the traffic status according to the travelling speed of probe vehicles. We then develop an integer programming model with a set of novel constraints to estimate the spatiotemporal region impacted by the incident. Unlike existing studies that only distinguish between uncongested and congested status, our model allows us to determine the impact region with diverse congestion levels. We validate our model using both simulation and real data. Results demonstrate that our approach can not only ensure the consistency of the propagation of shockwaves even when multiple congestion levels are incorporated, but also produce more accurate estimation of the delay caused by the incident when compared to the current state-of-the-art approach.
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http://dx.doi.org/10.1016/j.aap.2021.106255 | DOI Listing |
Front Immunol
January 2025
Department of Otolaryngology, Changhai Hospital, Naval Medical University, Shanghai, China.
Background: There is no consensus regarding the optimal regimen for metastatic nasopharyngeal carcinoma (dmNPC). Locoregional intensity modulated radiotherapy (LRRT) following palliative chemotherapy (PCT) has been shown to prolong the overall survival (OS) and improve the progression-free survival (PFS) of patients with dmNPC, compared with PCT alone. However, patients with a high tumor burden do not benefit from additional LRRT, which inevitably results in toxicity.
View Article and Find Full Text PDFEur J Intern Med
January 2025
Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy; Division of Cardiology, AOU Maggiore della Carità, Novara, Italy. Electronic address:
Aims: Data on the early use of sodium-glucose co-transporter 2 inhibitors (SGLT2i) in patients with acute heart failure (HF) are conflicting, and mostly evaluating soft endpoints (i.e., indices of congestion, renal function, ejection fraction, and diuresis).
View Article and Find Full Text PDFAccid Anal Prev
January 2025
School of Automotive and Transportation Engineering, Hefei University of Technology, Hefei 230009 China. Electronic address:
Freeway continuous merging areas in a short distance exist continuous multiple ramps. In these areas, traffic flow and vehicle interactions are more complex, and traffic crashes and congestion are more frequent, which has been a major concern influencing traffic operation of freeways. Active traffic management (ATM) measures can improve traffic efficiency and reduce traffic risks in merging areas.
View Article and Find Full Text PDFEndocr Metab Immune Disord Drug Targets
January 2025
Department of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 324 Jingwu Weiqi Rd, Jinan, 250021, China.
Background And Aim: In the context of gastrointestinal diseases, the role of monoacylglycerol lipase (MAGL) is significant. Therefore, the objective of this study was to examine the protective effects of MAGL inhibition using JZL184 in rat models of severe acute pancreatitis (SAP) and to explore its mechanism.
Methods: In this study, a rat model of SAP was established, and the rats were divided into three groups for treatment: the Control group (CON), the SAP group (SAP), and the SAP group treated with JZL184 (JZL184).
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