Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238451PMC
http://dx.doi.org/10.1016/S2666-5247(21)00157-9DOI Listing

Publication Analysis

Top Keywords

paucity discordance
4
discordance neutralising
4
neutralising antibody
4
antibody responses
4
responses sars-cov-2
4
sars-cov-2 vocs
4
vocs vaccinated
4
vaccinated immunodeficient
4
immunodeficient patients
4
patients health-care
4

Similar Publications

Chimeric antigen receptor T-cell (CAR-T) therapy has emerged as a breakthrough treatment for relapsed and refractory multiple myeloma (RRMM). However, these products are complex to deliver and alternative options are now available. Identifying biomarkers that can predict therapeutic outcomes is crucial for optimizing patient selection.

View Article and Find Full Text PDF

Fish early-stages constitute useful indicators of the states of marine ecosystems, as well as important fishery resources. Given the spectacular phenotypic changes during ontogeny, and the paucity of diagnostic morphological characters at the species level, the identification of fish early-stages is a challenging task. DNA barcoding, the use of the mitochondrial gene of the cytochrome c oxidase subunit I (COI) as an internal species tag, opened new perspectives for the identifications of both larval fish and fish eggs.

View Article and Find Full Text PDF

Transitioning Adolescents and Young Adults with Lipid Disorders to Adult Health Care.

Curr Atheroscler Rep

December 2024

Department of Pediatrics, Division of Cardiology, University of Tennessee Health Science Center, Le Bonheur Children's Hospital, 49 N. Dunlap St, Memphis, TN, 38103, USA.

Article Synopsis
  • Pediatric healthcare providers recognize the need for effective transition strategies for adolescents with chronic conditions, but there's limited published data on how to effectively transition youth with lipid disorders, who face a higher risk of heart disease.
  • Atherosclerosis can start early in life, yet there are no specific guidelines for transitioning adolescents and young adults with dyslipidemia, leading to uncertainty in their care.
  • Conflicting recommendations for lipid management in children versus adults create challenges, putting young adults at risk for worsening health issues and premature cardiovascular events.
View Article and Find Full Text PDF
Article Synopsis
  • Gastrulation is a crucial process in embryo development that organizes germ layers and sets up the body plan, where stem cell-derived models like gastruloids are used to study it.
  • Despite advances using techniques like single-cell RNA sequencing, there is a lack of understanding of protein dynamics in these models.
  • This study applies quantitative proteomics to analyze different stages of gastruloids, uncovering key insights into protein interactions and regulations that enhance our understanding of early mammalian development beyond what transcriptomics can offer.
View Article and Find Full Text PDF
Article Synopsis
  • The increasing use of interventional techniques in chronic pain patients on anticoagulant and antiplatelet therapy poses challenges in balancing the bleeding risk from these medications and the thrombosis risk from discontinuation.
  • Guidelines have been developed through a literature review and expert consensus to help assess and manage the risks of bleeding and thrombosis during interventional procedures for these patients.
  • These guidelines provide a framework for healthcare professionals to make informed decisions regarding the continuation or temporary suspension of anticoagulant and antiplatelet therapy in the context of interventional pain management.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!