AI Article Synopsis

  • - The novel coronavirus outbreak, which started in Wuhan, China, was declared a pandemic by the World Health Organization on March 11, 2020, highlighting the need to understand the risk factors affecting the disease's progression.
  • - Older adults (60+) with cardio metabolic risk factors such as obesity, hypertension, diabetes, and dyslipidemia are at greater risk for severe COVID-19 outcomes and increased mortality.
  • - This study reviews literature from the pandemic's onset to analyze how these risk factors influence COVID-19 severity and discusses the cyclical relationship between these conditions and the inflammatory response triggered by the virus.

Article Abstract

The novel coronavirus, which began spreading from China Wuhan and gradually spreaded to most countries, led to the announcement by the World Health Organization on March 11, 2020, as a new pandemic. The most important point presented by the World Health Organization about this disease is to better understand the risk factors that exacerbate the course of the disease and worsen its prognosis. Due to the high majority of cardio metabolic risk factors like obesity, hypertension, diabetes, and dyslipidemia among the population over 60 years old and higher, these cardio metabolic risk factors along with the age of these people could worsen the prognosis of the coronavirus disease of 2019 (COVID-19) and its mortality. In this study, we aimed to review the articles from the beginning of the pandemic on the impression of cardio metabolic risk factors on COVID-19 and the effectiveness of COVID-19 on how to manage these diseases. All the factors studied in this article, including hypertension, diabetes mellitus, dyslipidemia, and obesity exacerbate the course of Covid-19 disease by different mechanisms, and the inflammatory process caused by coronavirus can also create a vicious cycle in controlling these diseases for patients.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233632PMC
http://dx.doi.org/10.1007/s40200-021-00822-2DOI Listing

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