Characteristics of Malignant Thyroid Tumors: A Retrospective Study on 320 Patients.

Acta Clin Croat

1Department of Otorhinolaryngology and Maxillofacial Surgery, Osijek Medical Faculty, J.J. Strossmayer Osijek University, J. Huttlera 4, Osijek, Croatia; 2Department of Otorhinolaryngology and Head and Neck Surgery, Osijek Clinical Hospital Centre, J. Huttlera 4, Osijek, Croatia; 3Department of Otorhinolaryngology, Vukovar General Hospital, Županijska ul. 35, Vukovar, Croatia.

Published: June 2020

Papillary thyroid cancer accounts for 80-85% of diagnosed thyroid cancers, while follicular, medullary, and anaplastic cancers are diagnosed significantly less frequently. This study aimed to show the characteristics of malignant thyroid tumors. In this retrospective study, we analyzed data from 320 patients who underwent thyroid surgery from January 2018 to December 2019. We recorded and statistically analyzed basic demographic data, data of the cytological and pathohistological findings, and tumor characteristics (size, multifocality, extrathyroidal and lymphovascular invasion). Thyroid cancer was diagnosed in 95 patients. The incidence of thyroid cancer was higher in women than in men, but without a significant difference (p=0.46). There was a significant difference between preoperative cytological findings and definitive pathohistological diagnosis (p=0.001). There was no significant difference between genders in tumor size, extrathyroidal and lymphovascular invasion, and multifocality. There were significantly more thyroid cancers with a lymphovascular invasion that were less than 2 cm in size (p=0.04). In our opinion, it is important to emphasize the value of early diagnostics and analysis of the malignant tumor characteristics that are major prognostic factors for survival in patients with thyroid cancer.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212610PMC
http://dx.doi.org/10.20471/acc.2020.59.s1.14DOI Listing

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