Surgical Treatment of Recurrent Metastatic Parathyroid Gland Carcinoma.

Acta Clin Croat

1University of Split, Split University Hospital Center, Department of Otorhinolaryngology, Split, Croatia; 2University of Split, Split University Hospital Center, Department of Endocrinology, Split, Croatia.

Published: June 2020

AI Article Synopsis

  • A 48-year-old man underwent surgery for recurrent metastatic parathyroid gland carcinoma in his neck, following an initial surgery for the same condition 28 months earlier.
  • The surgical procedure involved removing the metastases along with the enlarged lower left parathyroid gland to reduce the risk of hypercalcemia and cancer recurrence, given the embryos' similarity in developing multiple tumors.
  • Post-surgery, the patient received radiation therapy to further mitigate the chances of cancer recurrence and manage potential complications related to high calcium levels.

Article Abstract

Aim: We present the case of a 48-year-old male patient who underwent surgery for a recurrent metastatic parathyroid gland carcinoma in the patient's right paratracheal space of the neck. The patient had undergone surgery for lower right parathyroid gland carcinoma 28 months earlier.

Results: The metastases were resected with an ipsilateral central neck dissection and with the removal of the enlarged lower left parathyroid gland. After exploration of the remnant parathyroid glands we noticed that lower left parathyroid gland was macroscopically enlarged so we decided to remove it to prevent possible hypercalcemia in future and to also prevent possible recurrence of cancer or development of a new primary, considering the identical embryological origin of the lower parathyroid glands and possibility of synchronous, multiple tumors, which generally follow the same embryological origin if they occur. The patient was also treated with radiation therapy after the surgery.

Conclusion: With the present surgical approach to recurrent metastatic parathyroid gland carcinoma, we aimed to prevent the recurrence of cancer or development of new primary and prevent or delay hypercalcemia in the future with all severe adverse metabolic states associated with high serum calcium levels.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8212600PMC
http://dx.doi.org/10.20471/acc.2020.59.s1.12DOI Listing

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