The Tien Shan and Pamir mountains host over 28,000 glaciers providing essential water resources for increasing water demand in Central Asia. A disequilibrium between glaciers and climate affects meltwater release to Central Asian rivers, challenging the region's water availability. Previous research has neglected temporal variability. We present glacier mass balance estimates based on transient snowline and geodetic surveys with unprecedented spatiotemporal resolution from 1999/00 to 2017/18. Our results reveal spatiotemporal heterogeneity characterized by two mass balance clusters: (a) positive, low variability, and (b) negative, high variability. This translates into variable glacial meltwater release (≈1-16%) of annual river runoff for two watersheds. Our study reveals more complex climate forcing-runoff responses and importance of glacial meltwater variability for the region than suggested previously.
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http://dx.doi.org/10.1029/2020GL092084 | DOI Listing |
Mol Neurobiol
December 2024
Senior Department of Otolaryngology-Head & Neck Surgery, the Sixth Medical Center of PLA General Hospital, Beijing, 100853, China.
Noise exposure is one of the most common causes of sensorineural hearing loss. Although many studies considered inflammation to be a major contributor to noise-induced hearing loss, the process of cochlear inflammation is still unclear. Studies have found that activation of the NF-κB signaling pathway results in the accumulation of macrophages in the inner ear plays an important role in hair cell damage.
View Article and Find Full Text PDFEur J Appl Physiol
December 2024
Institut Nacional d'Educació Física de Catalunya (INEFC), Universitat de Barcelona (UB), 08038, Barcelona, Spain.
Purpose: The aim of this study was to determine whether a soccer match affects the rapid force-generating capacity of the hamstring muscles, given their key role in both horizontal ground reaction force production during sprint biomechanics, and in the deceleration of the shank during the late swing phase, where rapid force production is essential owing to time constraints. Therefore, the research objective was to determine soccer match-induced hamstrings residual fatigue and recovery through rate of torque development (RTD) and associated biochemical parameters.
Methods: The recovery kinetics of hamstrings RTD metrics by the 90°:20° test, together with serum biomarkers (creatine kinase, mitochondrial creatine kinase, transaminases, malondialdehyde, irisin), were assessed in 19 male, regional first-division soccer players (age = 20.
BMJ Paediatr Open
December 2024
Department of Pediatrics, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Introduction: Maternal undernutrition and inflammation in utero may significantly impact the neurodevelopmental potential of offspring. However, few studies have investigated the effects of pregnancy interventions on long-term child growth and development. This study will examine the effects of prenatal nutrition and infection management interventions on long-term growth and neurodevelopmental outcomes of offspring.
View Article and Find Full Text PDFPediatr Nephrol
December 2024
Department of Physical Medicine and Rehabilitation, Medical Faculty, Ondokuz Mayis University, Samsun, Turkey.
Background: The study evaluated the relationship between balance function and skeletal muscle mass index (ASMI), physical function, and fatigue in children with chronic kidney disease (CKD).
Methods: A cross-sectional study of 83 children with CKD (stages 1-4, dialysis, transplant) and 71 healthy controls was conducted. Functional performance tests, including gait speed, 6-min walk distance (6MWD), five-repetition sit-to-stand (5RST), and timed up-and-go (TUG) tests, were administered.
Cureus
November 2024
Department of Therapeutic Processes, Faculty of Health Sciences, Universidad Católica de Temuco, Temuco, CHL.
Background: Contradictory data are available on the possible association between sarcopenia and other clinical disorders in patients with chronic kidney disease (CKD) undergoing hemodialysis.
Objective: To determine the association between sarcopenia and markers associated with systemic inflammation, fasting glycemia, and quality of life in older people with CKD undergoing hemodialysis.
Methods: This was an analytical cross-sectional study.
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