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http://dx.doi.org/10.1111/ijd.15772 | DOI Listing |
Am J Surg Pathol
December 2023
Diagnostic and Research Institute of Pathology, Medical University Graz, Graz, Austria.
Compared with vulva, precursor lesions of human papillomavirus (HPV)-independent invasive squamous cell carcinoma (SCC) of the penis are insufficiently characterized. We analyzed the histologic and immunohistochemical characteristics of 70 peritumoral precursor lesions and correlated them with the histology and mutational profile of the adjacent HPV-negative invasive penile SCC. Atypical basal keratinocyte proliferation with variously elongated epithelial rete with premature squamatiziation, but regular superficial cornification, termed differentiated penile intraepithelial neoplasia (d-PeIN), were identified adjacent to 42/70 (60%) SCC (36/42 keratinizing ( P <0.
View Article and Find Full Text PDFDermatologie (Heidelb)
March 2023
Universitäts-Hautklinik Tübingen, Eberhard-Karls-Universität, Liebermeisterstr. 25, 72076, Tübingen, Deutschland.
A 59-year-old man presented with a growing tumor on the glans penis, which we excised. Histologically, there was an acanthotic epidermis under which the papillary dermis was filled with foamy macrophages, best seen in a CD 68 stain. Verruciform xanthoma was diagnosed.
View Article and Find Full Text PDFInt J Dermatol
February 2022
Department of Pathology, Ho Chi Minh City University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam.
Clin Med Insights Case Rep
April 2021
Department of oncologic surgery, Salah Azaiz Institute, Tunis, Tunisia.
Warty squamous cell carcinoma (WSCC), is a rare variant of squamous cell carcinoma that occurs mostly in younger women, but can occur in old women. It is due to human papillomavirus (HPV) infection. This rare entity has been described in several organs such as vulva, cervix, and penis.
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