Male genital lichen planus: A retrospective study of 89 cases.

Ann Dermatol Venereol

Dermatology Department, Saint-Louis University Hospital, AP-HP, 1, avenue Claude-Vellefaux, 75010 Paris, France. Electronic address:

Published: March 2022

Background: Unlike other types of lichen planus (LP), there are no series concerning male genital LP.

Objective: To describe the clinical characteristics, diagnosis, and response to treatment of male genital LP.

Patients And Methods: A retrospective study of male patients with genital LP consulting a dermatologist specialized in anogenital diseases between January 2010 and 2019. Demographic data, history, functional signs, clinical characteristics, pathology, complications, and treatment efficacy were collected.

Results: Eighty-nine patients were included at four centers. The median age was 51 years. Most patients were uncircumcised and asymptomatic. In 88.8% of cases, only the genital mucosa was involved. Erythema (71%), papules (21.3%), lacy network (15.7%), atrophic lesions (15.7%), erosions (14.6%), and post-inflammatory hyperpigmentation (2.2%) were less frequently observed. Biopsy results confirmed LP in 61.3% of cases but could not rule out other inflammatory genital dermatoses in other cases. Anatomic complications were observed in 30.3% of patients. Topical corticosteroids (TCS) induced remission in most cases. Tacrolimus efficacy was comparable to that of TCS.

Conclusion: Male genital LP is a rare inflammatory disorder chiefly affecting uncircumcised men. It is found predominantly on the mucosal component of the penis and presents as non-erosive inflammatory balanitis in most cases, with frequent partial or complete remission on treatment with TCS.

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http://dx.doi.org/10.1016/j.annder.2021.04.007DOI Listing

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