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Hematoporphyrin Derivative-Photodynamic Therapy (HpD-PDT) for Extensive Vulvar and Vaginal Bowen's Disease: A Case Report.
Photodiagnosis Photodyn Ther
December 2024
First Affiliated hospital of Heilongjiang University of Traditional Chinese Medicine,Department of peripheral vascular diseases,Harbin City, Heilongjiang Province, China. Electronic address:
Bowen's disease (BD) is an intraepithelial squamous cell carcinoma (SCC) that commonly affects older individuals, with the vulva being a prevalent site in women. Lesions within the vagina pose a particular challenge for surgical treatment, often compromising both functional integrity and cosmesis. Photodynamic therapy (PDT) is an emerging, safe, and non-invasive technique utilizing a photosensitizer and a specific light source, widely applied in the treatment of malignancies and skin diseases.
View Article and Find Full Text PDFFrom Plasmacytoma to Rib Tuberculosis: The Case of A Breast Mass With An Unexpected Diagnosis.
Eur J Breast Health
January 2025
Department of Pathology, University of Sousse Faculty of Medicine of Sousse, Farhat Hached Teaching Hospital, Sousse, Tunisia.
Tuberculosis (TB) of the rib is an uncommon manifestation of extrapulmonary TB that can pose significant diagnostic challenges, especially when presenting as a breast mass. We report the case of a 74-year-old woman who presented with a left breast lump, initially suspected to be a plasmacytoma due to its imaging characteristics and clinical history. The mass was surgically excised, and histopathological analysis revealed granulomatous inflammation with caseous necrosis, suggesting TB.
View Article and Find Full Text PDFInfective Endocarditis With Origin in Orbital Vascular Malformation and Maxillary Sinusitis: A Case Report and Review of Four Patients in the Literature.
Cureus
November 2024
Department of Internal Medicine, Ochiai Hospital, Maniwa, JPN.
Infective endocarditis is a life-threatening disease and the early diagnosis is crucial for a better outcome. We report an old adult who developed infective endocarditis in association with new-onset maxillary sinusitis as well as proptosis, which was caused by an orbital mass lesion in the background of pre-existing orbital vascular malformation. A 74-year-old woman was found incidentally to have right orbital vascular (venous) malformation by head magnetic resonance imaging when she was hospitalized for left dorsal pontine infarction.
View Article and Find Full Text PDFA Case of Fat Embolism Syndrome Treated with Methylprednisolone.
Intern Med
December 2024
Department of Cardiovascular Medicine, Kyoto University Hospital, Japan.
A 74-year-old woman presented with sudden dyspnea 22 h after orthopedic surgery. Echocardiography revealed significant right ventricular dilatation, suggesting the development of acute pulmonary embolism. However, contrast computed tomography showed no signs of pulmonary thromboembolism, leading to suspicion of fat embolism syndrome (FES).
View Article and Find Full Text PDFAlectinib for the treatment of papillary thyroid carcinoma harbouring STRN - ALK fusion.
Eur J Cancer
December 2024
Department of Oncology, Azienda Sanitaria Universitaria Friuli Centrale (ASUFC), Udine, Italy. Electronic address:
Background: Anaplastic Lymphoma Kinase (ALK) rearrangement is a rare alteration in differentiated thyroid carcinomas (DTCs). Due to its low prevalence, a few evidence are available about the use of ALK inhibitors in advanced DTCs.
Methods: We report the case of a striatin (STRN) - ALK translocated advanced thyroid carcinoma.
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