Background: Smooth pursuit dysfunction is common in MS, but rarely quantified and may be missed on exam.
Methods: NeuroFitONE™ smooth pursuit performance measures were compared between MS (n = 20) and healthy control (n = 19) participants.
Results: Compared to controls, MS patients had lower proportion of smooth pursuit (0.63 vs. 0.73; p = 0.047), increased directional (10.1 vs. 8°; p = 0.014) and speed noise (4.3 vs. 3.1°/sec; p = 0.021) and reduced initiation acceleration (96.83 vs. 115.33°/sec; p = 0.061). Significant univariate correlations with clinical scores (EDSS, T25-FW) were observed.
Conclusion: Smooth pursuit dysfunction in MS can be readily quantified and distinguishes MS eyes from healthy controls.
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| http://dx.doi.org/10.1016/j.msard.2021.103073 | DOI Listing |
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