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Epidemiology of New Psychoactive Substances in Relation to Traditional Drugs of Abuse in Clinical Oral Fluid Samples.

Basic Clin Pharmacol Toxicol

February 2025

Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

New psychoactive substances (NPS) are health-hazardous through unpredictable toxicity and effects and largely unknown epidemiology, motivating studies of the latter. Up to 138 NPS were retrospectively identified using liquid chromatography-high resolution mass spectrometry data from all 34 183 oral fluid drug samples collected in one Swedish health care region 2019-2020 representing 9468 psychiatric and addiction care patients. In total, 618 findings representing 58 NPS were detected in 481 samples from 201 patients.

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Management of female para-urethral cyst with dyspareunia: a case report.

J Med Case Rep

January 2025

Department of Urology, SRM Institute of Science and Technology, SRM Nagar, Chengalpattu, Kattankulathur, Tamilnadu, 603203, India.

Background: The diagnosis and management of female genital conditions (Rodriguez et al. in Clin Anat 34(1):103-107, 2020. https://doi.

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Au nanoclusters often demonstrate useful optical properties such as visible/near-infrared photoluminescence in addition to remarkable thermodynamic stability owing to their superatomic behavior. The smallest of the 8e- superatomic Au nanoclusters, Au11, has limited applications due to its lack of luminescence and relatively low stability. In this work, we investigate the introduction of a single Pt dopant to the center of a halide- and triphenylphosphine-ligated Au11 nanocluster, obtaining a cluster with a proposed molecular formula PtAu10(PPh3)7Br3.

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Purpose: Speech sound disorder (SSD) is one of the major speech disorders in school-age children. Given the heterogeneity in terms of subtypes within SSD, there is a need to develop techniques for a quick identification of these subtypes. Furthermore, given the paucity of studies from children with SSD from Cantonese-speaking homes and a noted prevalence of SSDs in Cantonese-speaking children, it becomes even more important to investigate the subtypes of SSDs in Cantonese-speaking children.

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Background And Aims: Cadherins are adhesion proteins, and their dysregulation may result in the development of atherosclerosis, plaque rupture, or lesions of the vascular wall. The aim of the present study was to detect the associations of cadherins-P, -E, and -H, with atherosclerosis and pathological cardiovascular conditions.

Methods And Results: The present study with 3-year follow up evaluated atherosclerosis and fasting levels of P-, E-, and H-cadherins in the serum samples of 214 patients in a hospital setting.

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