Computer-aided quantitative MSCT measurements may be useful for congenital lung malformations surgical approach selection.

Purpose: To examine the association between the MSCT quantitative measurements of congenital lung malformations (CLM) and the selection of surgical approaches (lobectomy vs. lung-sparing surgery).

Methods: This retrospective study evaluated CLM surgical cases at our institution from 2016 to 2018. MSCT quantitative measurements were generated by a semi-automated approach: the volume of the lesion (V), the volume of the lesion-involved lobe (V), the volume of the lesion-involved lung (V) and the volume of the total lung (V). The proportions of V to V (P), V to V (P), and V to V (P) were calculated. We used Logistics regression to examine whether quantitative measurements were associated with the selection of surgical approaches.

Results: 151 patients were included (median age at surgery 6 months). 82 patients underwent lung-sparing surgery, and 69 patients underwent lobectomy. V (OR 1.51, 95% CI 1.09-2.07), P (OR 1.78, 95% CI 1.16-2.72), P (OR 1.63, 95% CI 1.13-2.35), and P (OR 1.58, 95% CI 1.12-2.22) were positively associated with the selection of lobectomy.

Conclusion: The application of quantified MSCT analysis may provide insight into the quantitative characteristics of CLM, which could be potentially useful for surgical approach selection.