Introduction: Indocyanine green (ICG) angiography of the parathyroids is useful in prediction of postthyroidectomy hypocalcemia. We compared the diagnostic accuracy of a single-gland ICG score of 2 with a score estimated by adding the viability value of the four glands (4-ICG).

Methods: Fifty patients (66% women, median age 49.4 years) underwent total thyroidectomy with identification of all 4 glands. The degree of ICG was classified as 0, black (nonvascularized), 1, gray/heterogeneous (partially vascularized), and 2, white (well vascularized).

Results: The diagnostic accuracy of the optimal cut-off of the 4-ICG sum score ≤3 was 84% (95% CI 70.9-92.8) lower than the diagnostic accuracy of 92% (80.8-97.8) of the ICG score 2. Both scores identified 2 false negative cases, but the rates of false positives were lower with the ICG score 2 (18.2% vs. 57.1%).

Conclusions: Identification of single-gland ICG score of 2 has a higher diagnostic accuracy than 4-ICG sum score to predict immediate hypocalcemia after total thyroidectomy.

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http://dx.doi.org/10.1016/j.cireng.2021.06.012DOI Listing

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