AI Article Synopsis
- The study aimed to explore the link between dietary habits and the risk of hepatocellular carcinoma (HCC) in US adults, using data from 641 HCC cases and 1002 cancer-free controls.
- A vegetable-based diet was found to lower the risk of HCC, while a Western diet increased the risk, suggesting dietary choices play a significant role in HCC prevention.
- The research highlights the importance of considering dietary patterns in the context of HCC risk factors, reinforcing the potential for dietary interventions in health management.
Article Abstract
The objective of this study was to assess the association between dietary patterns and risk of hepatocellular carcinoma (HCC) among US adults in a hospital-based case-control study. We analyzed data from 641 cases and 1002 controls recruited at The University of Texas MD Anderson Cancer Center during 2001-2018. Cases were patients with a pathologically or radiologically confirmed new diagnosis of HCC; controls were cancer-free spouses of patients with cancers other than gastrointestinal, lung, liver, or head and neck cancer. Cases and controls were frequency-matched by age and sex. Dietary patterns were identified by principal component analysis. Odds ratios (ORs) and corresponding confidence intervals (CIs) were computed using unconditional logistic regression with adjustment for major HCC risk factors, including hepatitis B virus and hepatitis C virus infection. A vegetable-based dietary pattern was inversely associated with HCC risk (highest compared with lowest tertile: OR 0.66, 95% CI 0.46-0.94). A Western diet pattern was directly associated with HCC risk (highest compared with lowest tertile: OR 1.79, 95% CI 1.19-2.69). These findings emphasize the potential role of dietary intake in HCC prevention and clinical management.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230753 | PMC |
| http://dx.doi.org/10.3390/nu13062011 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Data Mining of Infertility and Factors Influencing Its Development: A Finding From a Prospective Cohort Study of RaNCD in Iran.
Health Sci Rep
January 2025
Research Center for Environmental Determinants of Health (RCEDH), Health Institute Kermanshah University of Medical Sciences Kermanshah Iran.
Background And Aims: Infertility, as defined by the World Health Organization, is the inability to conceive after 12 months of regular, unprotected intercourse. This study aimed to identify factors influencing infertility by applying data mining techniques, specifically rule-mining methods, to analyze diverse patient data and uncover relevant insights. This approach involves a thorough analysis of patients' clinical characteristics, dietary habits, and overall conditions to identify complex patterns and relationships that may contribute to infertility.
View Article and Find Full Text PDFSalt use patterns and heavy metal urinary excretion.
Front Nutr
January 2025
Clinical Center of Reproductive Medicine, Lianyungang Maternal and Child Health Hospital, Lianyungang, China.
Background: Salt usage patterns have been associated with a risk of multiple diseases; however, their relationship with heavy metal exposure has not been extensively studied.
Methods: This study analyzed survey data from 11,574 NHANES participants. Weighted linear regression models were used to examine the relationship between the type of salt used by participants, the frequency of adding salt at the table, and the frequency of adding regular or seasoned salt to cooking or food preparation, and urinary concentrations of 10 heavy metals.
Stay in the Game: Comprehensive Approaches to Decrease the Risk of Sports Injuries.
Cureus
December 2024
Physiotherapy and Physical Medicine, University of Dschang, Dschang, CMR.
Recurrent sports injuries present complex challenges that extend beyond the playing field, impacting athletes' physical well-being, mental resilience, and financial stability. This review outlines a comprehensive framework designed to prevent and manage these setbacks, empowering athletes to achieve sustained performance and recovery. This multidimensional issue requires an integrative approach encompassing physical rehabilitation, psychological resilience, and nutritional strategies.
View Article and Find Full Text PDFThe association between dietary inflammatory index and bone health in US adolescents: Analysis of the NHANES data.
Bone Rep
March 2025
Department of pediatrics, Liaocheng Second People's Hospital, Liaocheng 252600, China.
Introduction: Adolescents with a lower peak bone mineral density (BMD) and bone mineral content (BMC) have an elevated risk of osteoporosis in adulthood. The impact of diet on bone health, particularly its role in managing inflammation, which is a key factor in bone health, is gaining wider recognition. Despite evidence that anti-inflammatory diets can enhance bone health, the link between the dietary inflammatory index (DII) and bone health among US adolescents has not been thoroughly investigated.
View Article and Find Full Text PDFPro-inflammatory dietary pattern and the risk of female gout: sex-specific findings from three prospective cohort studies.
Arthritis Rheumatol
January 2025
Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, USA.
Objective: We aimed to determine whether a pro-inflammatory dietary pattern (mechanism-based diet) is associated with incident female gout among two large cohorts of US women.
Methods: We prospectively followed 79,104 women from Nurses' Health Study (NHS; 1984-2016) and 93,454 women from NHSII (1991-2017); 45,445 men from Health Professionals Follow-up Study (1986-2016) served as a comparison cohort. Validated food frequency questionnaires were used to calculate Empirical Dietary Inflammatory Pattern (EDIP; food-based index predictive of circulating inflammatory biomarkers) scores every 4-years.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!