A 9-year-old cat was referred with multiple, raised, ulcerative and non-ulcerative nodules in the periocular area, sclera and ear-base region, and on the ventral aspect of the tongue. In addition, a progressive ulcerative skin nodule on the tail was observed. Fine-needle aspirations of multiple nodules from the eyelid and sclera revealed the presence of histiocytes with numerous acid-fast intracellular bacilli. The replication of slowly growing mycobacteria in liquid media was detected from biopsied nodules after three months of incubation. The molecular characterization of the isolate identified as the cause of the infection. The cat was treated with a combination of surgical excision and a four-week course of antimicrobial therapy including rifampicin combined with clarithromycin. This is an unusual manifestation of feline leprosy and the first molecularly confirmed infection in a cat with ocular involvement in Europe. The successful combination of a surgical and antimycobacterial treatment regimen is reported.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226594 | PMC |
| http://dx.doi.org/10.3390/pathogens10060687 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Atypical presentation of disseminated mycobacteriosis due to Mycobacterium avium in an aged cat.
Aust Vet J
December 2024
Centre for Veterinary Education, The University of Sydney, Sydney, Australia.
In cats, mycobacteriosis tends to present in a syndromic manner, with cases either being due to tuberculosis (TB) (in countries where TB is endemic), one of the "leprosy-like" diseases affecting the skin and subcutis, panniculitis caused by infection of subcutaneous tissues generally with rapidly growing Mycobacteria spp. or widely disseminated granulomatous disease, which is usually caused by members of the Mycobacterium avium-intracellulare complex (MAC). Disseminated MAC disease is rare, but when it occurs, usually develops in immunocompromised hosts with defective cell-mediated immunity.
View Article and Find Full Text PDFUnusual Presentation of Feline Leprosy Caused by in the Alpine Region.
Pathogens
June 2021
Vetaugenblick.ch, Wiesentalstrasse 142, 7000 Chur, Switzerland.
A 9-year-old cat was referred with multiple, raised, ulcerative and non-ulcerative nodules in the periocular area, sclera and ear-base region, and on the ventral aspect of the tongue. In addition, a progressive ulcerative skin nodule on the tail was observed. Fine-needle aspirations of multiple nodules from the eyelid and sclera revealed the presence of histiocytes with numerous acid-fast intracellular bacilli.
View Article and Find Full Text PDFHuman pathogenic (former subtype I) with zoonotic potential isolated from a diseased indoor pet cat, Japan.
Emerg Microbes Infect
December 2021
Department of Mycobacteriology, Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Article Synopsis
- Nontuberculous mycobacterial (NTM) infections have become more common in humans recently.
- A notable species of NTM, which has been identified, was first isolated from a domestic cat in Japan.
- Genetic analysis reveals the cat's isolate is identical to human pathogenic strains, indicating a risk of transmission between animals and humans, highlighting the need for a "One Health" approach for managing NTM infections.
A One Health Approach to Combatting : Narrative Review of an Emerging Zoonotic Fungal Pathogen in South America.
J Fungi (Basel)
October 2020
Laboratory of Clinical Research on Dermatozoonoses in Domestic Animals, Evandro Chagas National Institute of Infectious Diseases, Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro 21040-360, Brazil.
Cat-transmitted sporotrichosis caused by has become a major public health concern and presents a distinct divergence from the traditional epidemiology of sporotrichosis. This emerging fungal pathogen spreads readily among cat populations, and human infections occur exclusively via zoonotic transmission. While sporotrichosis is an implantation mycosis that typically manifests as cutaneous lesions in humans and cats, severe extracutaneous manifestations are more common with than other species infections.
View Article and Find Full Text PDFEffects of a Peer-Led Intervention on HIV Care Continuum Outcomes Among Contacts of Children, Adolescents, and Young Adults Living With HIV in Zimbabwe.
Glob Health Sci Pract
December 2019
International Union Against Tuberculosis and Lung Disease, Paris, France.
Background: Africaid Zvandiri, in partnership with the Ministry of Health and Child Care (MOHCC) in Zimbabwe, implemented a comprehensive, peer-led program, focused on children, adolescents, and young adults living with HIV aged 0-24 years. The peers, known as community adolescent treatment supporters (CATS), are people living with HIV (PLHIV) aged 18-24 years who are trained and mentored to support their peers throughout the HIV care continuum through support groups, home visits, phone call reminders, and messages. We report the HIV care continuum outcomes (HIV testing uptake, antiretroviral therapy [ART] uptake, retention, and viral suppression) in a cohort of household contacts and sexual partners (aged younger than 25 years) of index children, adolescents, and young adults living with HIV identified by CATS from October 2017 to September 2018 in 24 districts of Zimbabwe.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!