Surveillance and control activities for virus-transmitting mosquitoes have primarily focused on dwellings. There is little information about viral circulation in heavily trafficked places such as schools. We collected and analyzed data to assess the presence and prevalence of dengue, chikungunya, and Zika viruses in mosquitoes, and measured indices in schools in Medellín (Colombia) between 2016-2018. In 43.27% of 2632 visits we collected adults, creating 883 pools analyzed by RT-PCR. 14.27% of pools yielded positive for dengue or Zika (infection rates of 1.75-296.29 for ). was more abundant and had a higher infection rate for all studied diseases. indices varied over time. There was no association between abundance and mosquito infection rates, but the latter did correlate with cases of arboviral disease and climate. Results suggest schools are important sources of arbovirus and health agencies should include these sites in surveillance programs; it is essential to know the source for arboviral diseases transmission and the identification of the most population groups exposed to these diseases to research and developing new strategies.
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http://dx.doi.org/10.3390/ijerph18116137 | DOI Listing |
Open Forum Infect Dis
January 2025
Department of Microbiology and Immunology, State University of New York Upstate Medical University, Syracuse, New York, USA.
Background: Dengue virus (DENV) is an arboviral pathogen found in >100 countries and a source of significant morbidity and mortality. While the mechanisms underpinning the pathophysiology of severe Dengue are incompletely understood, it has been hypothesized that antibodies directed against the DENV envelope (E) protein can facilitate antibody-dependent enhancement (ADE) of the infection, increasing the number of infected cells and the severity of disease in an exposed individual. Accordingly, there is interest in defining mechanisms for directly targeting DENV-infected cells for immunologic clearance, an approach that bypasses the risk of ADE.
View Article and Find Full Text PDFBMJ Glob Health
December 2024
Department of Health Sciences, University of Groningen, Groningen, Groningen, Netherlands.
PLoS Negl Trop Dis
November 2024
Laboratoire de Biologie et Santé, UFR Biosciences, Université Félix Houphouët-Boigny, Abidjan, Côte d'Ivoire.
N C Med J
June 2024
School of Health Sciences, Western Carolina University.
Background: La Crosse virus neuroinvasive disease (LACVND) is the most common cause of arboviral encephalitis in children within the United States; in North Carolina, it is the most prevalent endemic mosquito-borne disease in humans.
Methods: Here we report a surveillance summary of confirmed and probable LACVND during 2000-2020 using North Carolina Electronic Disease Surveillance System data, and we describe associated demographic characteristics, spatiotemporal distribution, clinical features, and mortality rates.
Results: A total of 355 cases (74.
Sci Total Environ
December 2024
Departamento de Inmunología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Coyoacán, Ciudad de Mèxico 04510, Mexico. Electronic address:
Bisphenol A (BPA) is a widely used industrial chemical found in various products, leading to human exposure through dietary and non-dietary sources. It acts as an endocrine disruptor, affecting reproductive processes in vertebrates by binding to estrogen receptors. While its effects on vertebrates have been extensively studied, much less is known about its impact on invertebrates.
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