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Do Salivary Bypass Tubes Reduce the Risk of Pharyngocutaneous Fistula after Laryngopharyngectomy-A Systematic Review and Meta-Analysis. | LitMetric

AI Article Synopsis

  • The study evaluated the impact of salivary bypass tubes (SBT) on the development of pharyngocutaneous fistulas (PCF) in patients post-laryngopharyngectomy, analyzing 20 studies with a total of 2946 patients.
  • SBT usage was associated with a trend toward lower PCF rates (22.2%) compared to those without SBT (35.3%), though the result was marginally significant (p = 0.057).
  • A focused analysis of five studies with 580 patients further suggested that SBT significantly reduced the risk of PCF formation, indicating a beneficial effect of SBT in surgical recovery.

Article Abstract

To evaluate the effect of salivary bypass tube (SBT) usage on the occurrence of pharyngocutaneous fistula (PCF) in patients after a laryngopharyngectomy, a total of 20 studies, published between 1988 and 2021, were identified including 2946 patients. We performed a meta-analysis assessing the risk of PCF occurrence in patients after SBT application compared to those without. PCF occurred in 26.8% of cases (669/2496) and SBT was applied in 33.0% of patients (820/2483). There was an overall trend towards lower PCF rates when using SBTs (22.2% vs. 35.3%; = 0.057). We further selected five studies, comprising 580 patients who underwent laryngopharyngectomies, for meta-analysis showing that application of SBT reduced the risk of PCF formation (OR 0.46; 95% CI 0.18-1.18; = 0.11). The meta-analysis demonstrates a beneficial effect of SBT insertion on PCF formation in patients after laryngopharyngectomy.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201015PMC
http://dx.doi.org/10.3390/cancers13112827DOI Listing

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