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2020 and 2021 have been unprecedented years due to the rapid spread of the modified severe acute respiratory syndrome coronavirus around the world. The coronavirus disease 2019 (COVID-19) causes atypical infiltrated pneumonia with many neurological symptoms, and major sleep changes. The exposure of people to stress, such as social confinement and changes in daily routines, is accompanied by various sleep disturbances, known as 'coronasomnia' phenomenon. Sleep disorders induce neuroinflammation, which promotes the blood-brain barrier (BBB) disruption and entry of antigens and inflammatory factors into the brain. Here, we review findings and trends in sleep research in 2020-2021, demonstrating how COVID-19 and sleep disorders can induce BBB leakage via neuroinflammation, which might contribute to the 'coronasomnia' phenomenon. The new studies suggest that the control of sleep hygiene and quality should be incorporated into the rehabilitation of COVID-19 patients. We also discuss perspective strategies for the prevention of COVID-19-related BBB disorders. We demonstrate that sleep might be a novel biomarker of BBB leakage, and the analysis of sleep EEG patterns can be a breakthrough non-invasive technology for diagnosis of the COVID-19-caused BBB disruption.
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http://dx.doi.org/10.3390/ijms22136917 | DOI Listing |
Worldviews Evid Based Nurs
April 2025
Department of Sports Science and Physical Education, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.
Background: Previous studies regarding mind-body exercise among people with breast cancer mostly focused on one type of mind-body exercise and provided conflicting results.
Aims: This paper aims to systematically synthesize the evidence hierarchy and examine the credibility of previous meta-analyses of different types of mind-body exercises.
Methods: We searched PubMed, Embase, Cochrane Library, Web of Science, and Epitemonikos from database inception to February 2nd, 2024, for meta-analyses of randomized controlled trials.
J Neuroendocrinol
March 2025
Department of Zoology, University of Allahabad, Prayagraj, India.
Extra-retinal photoreception is common across fish and avian species. In birds, the hypothalamus contains non-visual photoreceptors that detect light and regulate multiple endocrine systems. To date, light-dependent control of seasonal reproduction is one of the most well-studied systems that require deep brain photoreception.
View Article and Find Full Text PDFJ Comp Neurol
March 2025
Department of Neuroscience, Carleton University, Ottawa, Ontario, Canada.
The zona incerta (ZI) supports diverse behaviors including binge feeding, sleep-wake cycles, nociception, and hunting. Diverse ZI functions can be attributed to its heterogeneous neurochemical characterization, cytoarchitecture, and efferent connections. The ZI is predominantly GABAergic, but we recently identified a subset of medial ZI GABA cells that are marked by the enzyme tyrosine hydroxylase (TH) and produce dopamine (DA).
View Article and Find Full Text PDFEncephale
March 2025
Département de psychiatrie et d'addictologie, AP-HP, GHU Paris Nord, DMU Neurosciences, Hôpital Bichat - Claude Bernard, 75018 Paris, France; Centre ChronoS, GHU Paris - Psychiatry & Neurosciences, 1, rue Cabanis, 75014 Paris, France; Université Paris Cité, Inserm, NeuroDiderot, 75019 Paris, France.
Objectives: This European study explored the cultural and societal aspects of chronic insomnia by means of a survey undertaken in France, Germany, Italy, Spain, and the United Kingdom. The primary objectives were to understand the impact of insomnia on the daily lives of patients, both personally and professionally, and to evaluate the patients' perceptions and coping strategies thus identifying cultural differences in the management of this disorder.
Methods: Based on online panels targeting insomnia sufferers, the survey included 755 patients aged 35 to 65 years with moderate to severe insomnia for at least three months, occurring at least three times per week (DSM-5 criteria for insomnia disorder, ISI score 15-28).
ISA Trans
March 2025
School of Electrical Engineering and Computer Science, National University of Sciences and Technology (NUST), Islamabad, Pakistan. Electronic address:
Glucose acts as a fundamental energy source for cells and plays a pivotal role in various physiological processes, including metabolism, signaling, and cellular control. Maintaining precise regulation of blood glucose levels is crucial for overall health and equilibrium. To achieve this balance, insulin is administered either orally or through an artificial pancreas (AP) during sleep, utilizing control algorithms based on mathematical models to regulate blood glucose concentration (BGC).
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!