Biosensing Membrane Base on Ferulic Acid and Glucose Oxidase for an Amperometric Glucose Biosensor.

Molecules

Chemistry Department, Universidad Autónoma Metropolitana Unidad Iztapalapa, Av. San Rafael Atlixco 186, Leyes de Reforma 1ra Secc., 09340 Ciudad de Mexico, Mexico.

Published: June 2021

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Article Abstract

A biosensing membrane base on ferulic acid and glucose oxidase is synthesized onto a carbon paste electrode by electropolymerization via cyclic voltammetry in aqueous media at neutral pH at a single step. The developed biosensors exhibit a linear response from 0.082 to 34 mM glucose concentration, with a coefficient of determination R equal to 0.997. The biosensors display a sensitivity of 1.1 μAmM cm, a detection limit of 0.025 mM, and 0.082 mM as glucose quantification limit. The studies reveal stable, repeatable, and reproducible biosensors response. The results indicate that the novel poly-ferulic acid membrane synthesized by electropolymerization is a promising method for glucose oxidase immobilization towards the development of glucose biosensors. The developed glucose biosensors exhibit a broader linear glucose response than other polymer-based glucose biosensors.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8233774PMC
http://dx.doi.org/10.3390/molecules26123757DOI Listing

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