Plutonium 239 dioxide, with particle sizes of 1-2 micron, injected to Wistar rats intravenously in doses of 92.5, 46.3, and 23.2 kBq/kg body mass, increased the frequency of chromosome aberrations in myelokaryocytes by 3.7, 2.3 and 1.7 times, respectively, compared to spontaneous levels.

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