The load-bearing capacity of natural airfield pavement has a direct impact on the safety of air operations. Unfortunately, the field tests often indicate that the load-bearing capacity of natural airfield pavements is not sufficient. In this case, it is necessary to reinforce them in order to meet the requirements set out in international documents. It is important that the method of reinforcing the subsoil is fast and as noninvasively as possible. There are many methods of reinforcing the subsoil, however, they are expensive and time-demanding, which involves turning off the airport for a long time. Airfield geocells made of recycled plastics discussed in the article seem to be the optimal solution due to the quick implementation of their application by pressing into the existing natural pavement. The article presents the results of laboratory tests demonstrating that material in question is load-resistant and chemical-resistant, while field studies have confirmed that the airfield geocell made of the plastic in question improves the load carrying capacity of natural airfield pavement.
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http://dx.doi.org/10.3390/ma14133557 | DOI Listing |
J Cachexia Sarcopenia Muscle
February 2025
Aging and Metabolism Research Group, Korea Food Research Institute, Wanju-gun, Jeollabuk-do, Republic of Korea.
Background: Sarcopenia, characterized by a gradual decline in skeletal muscle mass and function with age, significantly impacts both quality of life and mortality. Autophagy plays a crucial role in maintaining muscle health. There is growing interest in leveraging autophagy to mitigate muscle ageing effects.
View Article and Find Full Text PDFJ Cachexia Sarcopenia Muscle
February 2025
Department of Bioactive Material Sciences, Research Center of Bioactive Materials, Jeonbuk National University, Jeonju, Republic of Korea.
Background: The cellular prion protein (PrP), a glycoprotein encoded by the PRNP gene, is known to modulate muscle mass and exercise capacity. However, the role of PrP in the maintenance and regeneration of skeletal muscle during ageing remains unclear.
Methods: This study investigated the change in PrP expression during muscle formation using C2C12 cells and evaluated muscle function in Prnp wild-type (WT) and knock-out (KO) mice at different ages (1, 9 and 15 months).
In Vitro Model
February 2022
Institute of Bioinformatics & Biotechnology, Savitribai Phule Pune University, Pune, India.
Purpose: The aggressive nature of a tumor is presumably its inherent one, but different environmental cues can manipulate it in many ways. In this context, the influence of metabolic stresses on tumor behavior needs to be analyzed to understand their far-reaching implications on tumor aggression and dormancy. This work investigates different facets of the tumor, such as tumorigenic capacity, tumor phenotype, and migration, under multiple metabolic stress conditions.
View Article and Find Full Text PDF(), a Gram-negative bacterium commonly found in aquatic environments, has the capacity to be transmitted to humans through consumption of contaminated fish, water, or seafood. In this study, we present a case report concerning a 77-year-old female patient who experienced an acute exacerbation of chronic heart failure, subsequently developing severe septic shock due to necrotizing fasciitis caused by . Infections caused by are more prevalent during warmer months, particularly in regions characterized by dense aquaculture or the presence of natural water bodies.
View Article and Find Full Text PDFLife Med
December 2024
Zhejiang Key Laboratory of Medical Epigenetics, School of Basic Medical Sciences, The Third People's Hospital of Deqing, Department of Cardiology, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou 311121, China.
Oxidative stress diminishes the functionality of hematopoietic stem cells (HSCs) as age advances, with heightened reactive oxygen species (ROS) levels exacerbating DNA damage, cellular senescence, and hematopoietic impairment. DDO1002, a potent inhibitor of the NRF2-KEAP1 pathway, modulates the expression of antioxidant genes. Yet, the extent to which it mitigates hematopoietic decline post-total body irradiation (TBI) or in the context of aging remains to be elucidated.
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