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Decoding the Role of Gut-Microbiome in the Food Addiction Paradigm. | LitMetric

Decoding the Role of Gut-Microbiome in the Food Addiction Paradigm.

Int J Environ Res Public Health

Center for Research in Molecular Medicine and Chronic Diseases, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria (IDIS), 15782 Santiago de Compostela, Spain.

Published: June 2021

AI Article Synopsis

Article Abstract

Eating behaviour is characterised by a solid balance between homeostatic and hedonic regulatory mechanisms at the central level and highly influenced by peripheral signals. Among these signals, those generated by the gut microbiota have achieved relevance in recent years. Despite this complex regulation, under certain circumstances eating behaviour can be deregulated becoming addictive. Although there is still an ongoing debate about the food addiction concept, studies agree that patients with eating addictive behaviour present similar symptoms to those experienced by drug addicts, by affecting central areas involved in the control of motivated behaviour. In this context, this review tries to summarise the main data regarding the role of the gut microbiome in eating behaviour and how a gut dysbiosis can be responsible for a maladaptive behaviour such as "food addiction".

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8297196PMC
http://dx.doi.org/10.3390/ijerph18136825DOI Listing

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