In this study, 3-benzoylisoxazolines were synthesized by reacting alkenes with various α-nitroketones using chloramine-T as the base. The scope of α-nitroketones and alkenes is extensive, including different alkenes and alkynes to form various isoxazolines and isoxazoles. The use of chloramine-T, as the low-cost, easily handled, moderate base for 1,3-dipolar cycloaddition is attractive.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227129 | PMC |
| http://dx.doi.org/10.3390/molecules26123491 | DOI Listing |
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