This study aims to investigate the effect of a preoperative telerehabilitation (PT) program on muscle strength, knee range of motion (ROM), and functional outcomes in candidates for total knee arthroplasty (TKA). Sixty patients (all women, mean age 70.53 ± 2.7 years) scheduled for bilateral TKA participated in this study. The PT and preoperative patient education (PE) groups participated in a 3-week intensive exercise program (30 min/session, 2 times/day, 5 days/week), whereas the control group received the usual care before TKA. Quadriceps muscle strength, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), ROM of knee flexion, pain, and time up-and-go (TUG) test time were evaluated at 4 weeks preoperatively, post-interventionally, and 6 weeks after TKA. Significant differences were found in the time-by-group interaction for 60°/s extension peak torque [F(4, 100) = 2.499, = 0.047, = 0.91], 180°/s extension peak torque [F(4, 100) = 3.583, = 0.009, = 0.125], ROM [F(4, 100) = 4.689, = 0.002, = 0.158], TUG time [F(4, 100) = 7.252, < 0.001, = 0.225], WOMAC pain [F(4, 100) = 9.113, < 0.001, = 0.267], WOMAC functional outcome [F(4, 100) = 6.579, < 0.001, = 0.208], and WOMAC total score [F(4, 100) = 10.410, < 0.001, = 0.294]. The results of this study demonstrate the early benefits of a PT program in elderly female patients with end-stage osteoarthritis. The PT program improved muscle strength, ROM, and functional outcomes before TKA, which contributed to better functional recovery after TKA.
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http://dx.doi.org/10.3390/ijerph18116071 | DOI Listing |
Int J Biol Macromol
January 2025
Beijing Key Laboratory of Lignocellulosic Chemistry, and Engineering Research Center of Forestry Biomass Materials and Energy, Ministry of Education, Beijing Forestry University, Beijing 100083, China. Electronic address:
Org Lett
December 2024
Department of Chemistry, The University of Texas at Austin, 100 East 24th Street, Austin, Texas 78712, United States.
Herein, we report the palladium-catalyzed borylation of aryl halides (iodides or bromides) under base-free conditions utilizing a commercially available Lewis acidic mediator, Zn(OTf). Under these conditions, an array of electronically and functional-group-diverse aryl iodides and bromides undergo borylation to afford the corresponding aryl boronic esters in ≤82% isolated yields. Mechanistic investigations are consistent with Zn(OTf) enabling transmetalation between a cationic Pd(II)-Ar intermediate and Bpin via halide abstraction.
View Article and Find Full Text PDFFood Sci Nutr
November 2024
Bioprocessing and Biodetection Laboratory, Department of Food Science and Engineering University of Tehran Karaj Iran.
Bioactive peptides and protein hydrolysates have gained considerable attention in the food industry and functional food markets due to their diverse health effects, including antioxidant, antihypertensive, and antidiabetic properties. This study aimed to produce combined soy and corn protein hydrolysates using Alcalase (Al), modification of Al-hydrolysates through sequential hydrolysis using Flavourzyme (Al-FL), cross-linking of Al-hydrolysates using microbial transglutaminase (MTGase) (Al-TG), and fractionation of Al-hydrolysates by ultrafiltration (UF) with molecular weight (MW) cut-off of 100 (Al-F4), 30 (Al-F3), 10 (Al-F2), and 2 kDa (Al-F1). Notably, the < 2 kDa fraction (Al-F1) showcased exceptional biological activities, including antioxidant (81.
View Article and Find Full Text PDFChemphyschem
November 2024
Institute of Nuclear and New Energy Technology, Tsinghua University, Beijing, 100084, China.
The synthesis of efficient oxygen evolution reaction (OER) catalysts that markedly reduce the overpotential over an extended period is crucial for electrolytic water splitting toward hydrogen production. A kind of Ni/Fe fluoride (hydroxide) nanocomposite OER catalyst is designed and prepared by a two-step method for the first time. The nanocomposite with the optimal OER performance (Ni : Fe precursor ratio of 9 : 1) is observed to possess a nanoparticle morphology with size of about 100 nm.
View Article and Find Full Text PDFKurume Med J
November 2024
Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine.
The treatment of the underlying cause of liver disease may potentially reverse hepatic fibrosis. However, it remains uncertain whether improvement in fibrosis can be observed in decompensated liver cirrhosis (LC). Here, we present a case of autoimmune hepatitis (AIH)-related LC in which histological improvement of fibrosis was achieved despite the presence of decompensated LC.
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