This paper proposes a new diagnostic method for sensor signals collected during semiconductor manufacturing. These signals provide important information for predicting the quality and yield of the finished product. Much of the data gathered during this process is time series data for fault detection and classification (FDC) in real time. This means that time series classification (TSC) must be performed during fabrication. With advances in semiconductor manufacturing, the distinction between normal and abnormal data has become increasingly significant as new challenges arise in their identification. One challenge is that an extremely high FDC performance is required, which directly impacts productivity and yield. However, general classification algorithms can have difficulty separating normal and abnormal data because of subtle differences. Another challenge is that the frequency of abnormal data is remarkably low. Hence, engineers can use only normal data to develop their models. This study presents a method that overcomes these problems and improves the FDC performance; it consists of two phases. Phase I has three steps: signal segmentation, feature extraction based on local outlier factors (LOF), and one-class classification (OCC) modeling using the isolation forest () algorithm. Phase II, the test stage, consists of three steps: signal segmentation, feature extraction, and anomaly detection. The performance of the proposed method is superior to that of other baseline methods.
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http://dx.doi.org/10.3390/s21113880 | DOI Listing |
Eur Heart J Cardiovasc Imaging
January 2025
Departments of Medicine (Division of Artificial Intelligence in Medicine), Biomedical Sciences and Imaging, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Aims: Proximal coronary artery calcium (CAC) may improve prediction of major adverse cardiac events (MACE) beyond the CAC score, particularly in patients with low CAC burden. We investigated whether the proximal CAC can be detected on gated cardiac computer tomography (CT) and whether it provides prognostic significance with artificial intelligence (AI).
Methods And Results: A total of 2016 asymptomatic adults with baseline CAC CT scans from a single site were followed up for MACE for 14 years.
Biomed Phys Eng Express
January 2025
Electronics and Communication Engineering, Rajiv Gandhi University, Rono Hills, Doimukh, ITANAGAR, Itanagar, Arunachal Pradesh, 791112, INDIA.
Accurate detection of cardiac arrhythmias is crucial for preventing premature deaths. The current study employs a dual-stage Discrete Wavelet Transform (DWT) and a median filter to eliminate noise from ECG signals. Subsequently, ECG signals are segmented, and QRS regions are extracted for further preprocessing.
View Article and Find Full Text PDFWorld J Gastrointest Oncol
January 2025
Department of Medical College, Jinan University, Guangzhou 510000, Guangdong Province, China.
Background: Gallbladder neuroendocrine carcinoma (NEC) represents a subtype of gallbladder malignancies characterized by a low incidence, aggressive nature, and poor prognosis. Despite its clinical severity, the genetic alterations, mechanisms, and signaling pathways underlying gallbladder NEC remain unclear.
Case Summary: This case study presents a rare instance of primary gallbladder NEC in a 73-year-old female patient, who underwent a radical cholecystectomy with hepatic hilar lymphadenectomy and resection of liver segments IV-B and V.
Kidney Int Rep
January 2025
Translational Science and Experimental Medicine, Early R&I, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Type I interferons (IFNs) are immunostimulatory molecules that can activate the innate and adaptive immune systems. In cases of immune dysfunction, prolonged activation of the type I IFN pathway has been correlated with kidney tissue damage in a wide range of kidney disorders, such as lupus nephritis (LN) and focal segmental glomerulosclerosis (FSGS). Genetic mutations, such as risk variants in conjunction with elevated type I IFN expression, are also associated with higher rates of chronic kidney disease in patients with LN and collapsing FSGS.
View Article and Find Full Text PDFMol Pharm
January 2025
Key Laboratory of Chemical Biology (Ministry of Education), NMPA Key Laboratory for Quality Research and Evaluation of Carbohydrate-based Medicine, Department of Pharmacology, School of Pharmaceutical Sciences, Shandong University, 44 Wenhua West Road, Jinan 250012, China.
Numerous diseases, such as diabetic retinopathy and age-related macular degeneration, can lead to retinal neovascularization, which can seriously impair the visual function and potentially result in blindness. The presence of the blood-retina barrier makes it challenging for ocularly administered drugs to penetrate physiological barriers and reach the ocular posterior segments, including the retina and choroid. Herein, we developed an innovative bifunctional peptide, Tat-C-RP7, which exhibits excellent penetration capabilities and antiangiogenic properties aimed at treating retinal neovascularization diseases.
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