Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 176
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 1034
Function: getPubMedXML
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3152
Function: GetPubMedArticleOutput_2016
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Uric acid (UA), as the final product of purine metabolism, exists in urine and serum, which plays an important role in human metabolism, immunity and other functions. The sensitive, efficient, and rapid detection of UA has far-reaching significance in clinical diagnosis and disease prevention. Herein, a novel coordination polymer constructed by dual-ligand was successfully prepared, which exhibited excellent thermal and water stability. The polymer was interlaced by coordination bonds and hydrogen bonds to form an infinitely extended three-dimensional framework, which showed a rare and novel topological structure. The complex selectively recognized UA through significant fluorescence quenching response in the presence of various interferences. The excellent detection sensitivity (the limited detection of 1.2 μM), outstanding anti-interference ability and remarkable recyclability marked the complex to be a promising sensor material towards UA. In addition, the detection mechanism of UA by the complex was investigated in detail by combining density functional theory (DFT) and a variety of other analytical methods.
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Source |
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http://dx.doi.org/10.1016/j.saa.2021.120065 | DOI Listing |
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