Background: The WHO and UNICEF have suggested pasteurized donor milk (PDM) as the best alternative for infants who do not receive enough milk from their mothers. This study aimed to assess the short-term outcomes of launching the first mother's milk bank in North-West of Iran.
Methods: The present retrospective study included 366 premature infants (181 pre-launch and 185 post-launch) who were hospitalized in Al-Zahra Hospital of Tabriz, Iran. The study included infants with birth weight ˂2000 g and/or gestation age ˂32 weeks who were born before and after the launch of mother's milk bank. Frequency of necrotizing enterocolitis (NEC), retinopathy of prematurity (ROP), late onset sepsis (LOS) and mortality rate were compared. Data were analyzed using SPSS 23 with the chi-square test, Fisher exact test, independent t test, and logistic regression test.
Results: In total, NEC grade ≥2 was reported in 9 cases; 8 cases (4.41%) in pre-launch and one case (0.54%) in post-launch (adjusted OR=0.091; 95% CI=0.010 to 0.849, =0.035). ROP was reported in 21 cases in two groups. Nineteen cases (10.5%) belonged to the pre-launch group and 2 cases (3.7%) to the post-launch group (adjusted OR=0.105; 95% CI=0.022 to 0.488, =0.004). LOS was also found in 17 cases (9.39%) in the pre-launch group and 4 cases (2.16%) in the post-launch period, suggesting a significant difference between the two groups (adjusted OR=0.297; 95%CI=0.089 to 0.995, =0.049). There was no significant difference in mortality of infants during hospitalization between the two groups (=0.789); however, it was decreased from 15 to 8.
Conclusion: Launching the human milk bank significantly improved the outcomes of premature infants.
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http://dx.doi.org/10.34172/aim.2021.57 | DOI Listing |
BMJ Open Qual
January 2025
Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, Pune, Maharashtra, India.
Background: Human milk banks (HMBs) offer the best feed for neonates after mother's own milk (MOM), especially when MOM is insufficient. Although HMBs are founded on standard protocols, contamination and wastage of milk due to positive milk cultures remain a problem. Present study was planned as a quality improvement (QI) initiative to reduce culture rates at the HMB.
View Article and Find Full Text PDFMicroorganisms
December 2024
School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Rua Prof. Doutor Walter Maurício Correa, s/n, Botucatu 18618-681, Brazil.
Breastfeeding is fundamental for the development and protection of the newborn, and microorganisms present in breast milk are associated with the development of the infant's intestinal microbiota. However, there are factors that interfere with breastfeeding, resulting in the need to supply donated milk to milk banks for these children. Even though there is a restriction on medications prescribed for pregnant and breastfeeding women, some antimicrobials are accepted, as long as they are used correctly and as they can increase the selection pressure for resistant bacteria.
View Article and Find Full Text PDFJ Trop Med
January 2025
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Silymarin is a polyphenolic flavonoid extracted from milk thistle. It has potent immunomodulatory effects and can inhibit the replication of influenza A virus (IAV). The present study aimed to determine the inflammatory and anti-inflammatory cytokine secretion patterns in mice before and after silibinin treatment.
View Article and Find Full Text PDFSci Rep
January 2025
Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
The willingness to donate milk is influenced by maternal behavior, and the Theory of Planned Behavior is recognized as a significant predictor of this action. This study aims to identify the factors associated with milk donation among pregnant women based on the Theory of Planned Behavior. This descriptive and analytical cross-sectional study utilized stratified and convenience sampling methods on 337 pregnant women attending women's health and midwifery clinics affiliated with Mashhad University of Medical Sciences in 2024.
View Article and Find Full Text PDFRev Esc Enferm USP
January 2025
Universidade Federal de São Paulo, Escola Paulista de Enfermagem, Departamento de Enfermagem na Saúde da Mulher, São Paulo, SP, Brazil.
Objective: To analyze the factors associated with the hygienic-sanitary quality of donated human milk in terms of the donor profile and pumping site.
Method: Cross-sectional study with retrospective data collection of records of human milk samples donated to a Human Milk Bank in São Paulo, Brazil, from 2014 to 2019. Characteristics of human milk donors, pumping site, and hygienic-sanitary quality were analyzed based on the Standards of the Brazilian Human Milk Bank Network.
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