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http://dx.doi.org/10.1038/s41418-021-00826-8 | DOI Listing |
Phytomedicine
December 2024
School of Pharmaceutical Science, Department of Laboratory Medicine of Fenyang College, Shanxi Medical University, Taiyuan 030001, China. Electronic address:
Background: Alcoholic liver disease (ALD) is a significant contributor to liver damage. However, the clinical options for the treatment of ALD are limited. Astragaloside IV (AST-IV) is a saponin isolated from Astragalus membranaceus (AM).
View Article and Find Full Text PDFInt J Mol Sci
October 2023
Guangdong Provincial Key Laboratory of Brain Function and Disease, Pain Research Center, Department of Physiology, Zhongshan Medical School, Sun Yat-Sen University, 74 Zhongshan Road 2, Guangzhou 510080, China.
The hyperexcitability of the anterior cingulate cortex (ACC) has been implicated in the development of chronic pain. As one of the key causes of ACC hyperexcitation, disinhibition of the ACC may be closely related to the dysfunction of inhibitory parvalbumin (PV)-expressing interneurons (PV-INs). However, the molecular mechanism underlying the ACC PV-INs injury remains unclear.
View Article and Find Full Text PDFFront Pharmacol
August 2023
Institute of Medicinal Biotechnology, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
[This corrects the article DOI: 10.3389/fphar.2023.
View Article and Find Full Text PDFMicrobiol Spectr
August 2023
College of Veterinary Medicine, Northeast Agricultural University, Harbin, Heilongjiang Province, China.
The host-bacterial interactions play the key role in inflammatory bowel disease (IBD). Dysbiosis of the intestinal flora can lead to pathological changes in the intestine. Rosmarinic acid (RA) is a natural phenolic acid compound with antioxidant, anti-cancer, anti-inflammatory, anti-apoptotic, anti-fibrotic, and anti-bacterial activities that has a palliative effect on acute IBD.
View Article and Find Full Text PDFMetab Brain Dis
August 2023
Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education, and Research (NIPER), Hyderabad, Telangana, 500037, India.
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