AI Article Synopsis
- A study analyzed the effectiveness of quenching probe PCR (Q-probe PCR) in detecting macrolide-resistant Mycoplasma pneumoniae (MP) in 21 children with MP infections.
- Results showed that 66.7% of the cases were resistant to macrolide antibiotics, and those patients experienced a longer fever duration after initial treatment compared to those with sensitive strains.
- The study concluded that using Q-probe PCR can help in selecting the right antibiotics and may reduce fever duration in MP infections.
Article Abstract
To investigate the usefulness of quenching probe polymerase chain reaction (Q-probe PCR) for the detection of macrolide-resistant Mycoplasma pneumoniae (MP), we retrospectively analyzed the clinical course of 21 children with MP infection. The rate of macrolide-resistant MP was 66.7%. The duration of pyrexia after the initial antibiotic treatment was longer in patients with macrolide-resistant MP infection than in those with macrolide-sensitive MP infection. The duration of pyrexia after Q-probe PCR was not significantly different between patients with macrolide-resistant and -sensitive MP infection. Antibiotic use based on qPCR may reduce the duration of pyrexia. Q-probe PCR is useful in determining the appropriate antibiotics and improves the clinical course of MP infections.
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| http://dx.doi.org/10.7883/yoken.JJID.2021.003 | DOI Listing |
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