Background: The effects of varying levels of pre-operative opioids on post-operative outcomes following elective laparoscopic cholecystectomy is largely unknown.

Methods: Patients who underwent elective laparoscopic cholecystectomy from 2012 to 2019 were reviewed and categorized by the number of outpatient opioid prescriptions received in the 90 days preceding surgery: none (Naïve), one (1 Rx), two (2 Rx), or three or more (Chronic). Operative time, hospital length of stay, and 30-day readmission rate were analyzed.

Results: Of the 11911 patients identified, 2958 (24.8%) used opioids pre-operatively. Among patients with an overnight admission, the Naïve, 1 Rx, and 2 Rx cohorts had a shorter length of stay compared to the Chronic cohort. The Naïve group had the lowest 30-day readmission rate (5.0%) followed by the 1 Rx (5.9%), 2 Rx and Chronic groups (9.1% and 8.7%, respectively) (p < 0.001).

Conclusions: Prevalence of pre-operative opioid use is high and warrants surgeon assessment to minimize adverse post-operative outcomes.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amjsurg.2021.06.011DOI Listing

Publication Analysis

Top Keywords

elective laparoscopic
12
laparoscopic cholecystectomy
12
outcomes elective
8
length stay
8
30-day readmission
8
readmission rate
8
pre-operative opioid
4
opioid exposure
4
exposure surgical
4
surgical outcomes
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!