This paper describes the design, fabrication, and feasibility of paper-based optode devices (PODs) for sensing potassium selectively in biological fluids. PODs operate in exhaustive mode and integrate with a handheld, smartphone-connected optical reader. This integrated measuring system provides significant advantages over traditional optode membranes and other paper-based designs, by obtaining a linear optical response to potassium concentration via a simple, stackable design and by harnessing a smartphone to provide an easy-to-use interface, thus enabling remote monitoring of diseases.
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http://dx.doi.org/10.1021/acs.analchem.1c00794 | DOI Listing |
Front Bioeng Biotechnol
August 2024
Chemistry Department, Faculty of Science, Cairo University, Giza, Egypt.
In recent years, ion-selective optodes (ISOs) have remarkably progressed, driven by innovative modern designs and nanomaterial integration. This review explored the development of modern ISO by describing state-of-the-art strategies to improve their sensitivity, selectivity, and real-time monitoring capacity. The review reported the traditional membrane based-optodes, and investigated the latest research, current design principles, and the use of essential components, such as ionophores, indicator dyes, polymer membranes, and nanomaterials, in ISO fabrication.
View Article and Find Full Text PDFAnal Methods
February 2024
Department of Applied Chemistry, Faculty of Engineering, Shibaura Institute of Technology, 3-7-5 Toyosu, Koto-ku, Tokyo 135-8548, Japan.
The paper discusses the development of a low-cost, simple, and sensitive on-site measurement system for anionic surfactants (AS), specifically sodium alkylbenzene sulfonate (LAS), using a microfluidic paper-based analytical device (μPAD) with an optode as a detector. The need arises due to the discharge of AS-containing wastewater into natural environments, posing risks to aquatic organisms. Traditional methods for AS measurement have drawbacks like the use of harmful solvents, time-consuming procedures, and the need for expensive equipment, prompting the exploration of alternative approaches.
View Article and Find Full Text PDFAnal Bioanal Chem
November 2022
Department of Chemistry, Virginia Commonwealth University, Richmond, VA, 23284, USA.
We developed a paper-based colorimetric sensor for facile and cost-effective detection of Pb in drinking and environmental water samples. The Pb ion-selective optodes are fabricated by inkjet printing of ionophore, chromoionophore, and ion exchanger on cellulose paper. Pb in water samples induces deprotonation of the pH chromoionophore and changes the optode color, which is acquired and analyzed by a smartphone.
View Article and Find Full Text PDFAnal Chim Acta
August 2021
Department of Chemistry, Southern University of Science and Technology, Shenzhen, 518055, China. Electronic address:
Here, we present the optical detection of chloride ions with co-extraction based anion-selective optodes containing a BODIPY derivative (BDP-OH) and the ionophore In(OEP)Cl. Spectroscopic studies suggested that BDP-OH and In(OEP)Cl formed an adduct BDP-O-In(OEP), which was converted to BDP-OH and In(OEP)Cl upon increasing sample Cl concentration, and induced signal changes in both fluorescence and absorbance modes. The method was evaluated in polystyrene-graft-poly(ethylene oxide) (PS-PEO) nanospheres (ca.
View Article and Find Full Text PDFAnal Chem
July 2021
Jana Care, Inc., Boston, Massachusetts 02215, United States.
This paper describes the design, fabrication, and feasibility of paper-based optode devices (PODs) for sensing potassium selectively in biological fluids. PODs operate in exhaustive mode and integrate with a handheld, smartphone-connected optical reader. This integrated measuring system provides significant advantages over traditional optode membranes and other paper-based designs, by obtaining a linear optical response to potassium concentration via a simple, stackable design and by harnessing a smartphone to provide an easy-to-use interface, thus enabling remote monitoring of diseases.
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