In this paper, a terahertz (THz) biosensor based on all-metal metamaterial is theoretically investigated and experimentally verified. This THz metamaterial biosensor uses stainless steel materials that are manufactured via laser-drilling technology. The simulation results show that the maximum refractive index sensitivity and the figure of merit of this metamaterial sensor are 294.95 GHz/RIU and 4.03, respectively. Then, bovine serum albumin was chosen as the detection substance to assess this biosensor's effectiveness. The experiment results show that the detection sensitivity is 72.81 GHz/(ng/mm) and the limit of detection is 0.035 mg/mL. This THz metamaterial biosensor is simple, cost-effective, easy to fabricate, and has great potential in various biosensing applications.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245611 | PMC |
http://dx.doi.org/10.1186/s11671-021-03566-3 | DOI Listing |
Methods
December 2024
Department of Electrical and Computer Engineering at Georgia Tech Shenzhen Institute (GTSI), Shenzhen, Guangdong 518052, China; School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA. Electronic address:
Biosensors have many life sciences-related applications, particularly in the healthcare sector. They are employed in a wide range of fields, including drug development, food quality management, early diagnosis of diseases, and environmental monitoring. Terahertz-based biosensing has shown great promise as a label-free, non-invasive, and non-contact method of detecting biological substances.
View Article and Find Full Text PDFBiosens Bioelectron
November 2024
Department of Optoelectronic Engineering, College of Physics and Optoelectronic Engineering, Jinan University, Guangzhou, 510632, PR China; Guangdong Provincial Key Laboratory of Optical Fiber Sensing and Communications, Jinan University, Guangzhou, 510632, PR China; Key Laboratory of Optoelectronic Information and Sensing Technologies of Guangdong Higher Education Institutes, Jinan University, Guangzhou, 510632, PR China. Electronic address:
Surface plasmon resonance (SPR) optical fiber sensors are appealing for biomolecular detection due to their inherent characteristics such as flexibility, real-time performance, and high sensitivity. Concurrently, incorporating SPR sensors into wearable devices has emerged as a significant strategy. However, the majority of traditional SPR optical fiber sensors utilize spectrometers for optical readout, which leads to a relatively bulky overall size of the sensing system.
View Article and Find Full Text PDFBiosensors (Basel)
October 2024
Department of Physics and Department of Energy Systems Research, Ajou University, Suwon 16499, Republic of Korea.
Sci Rep
November 2024
Department of Electrical and Electronics Engineering, College of Science and Technology, University of Rwanda, Kigali, Rwanda.
Breast cancer is the most common malignancy in women globally, stemming from gene mutations that prompt irregular cellular growth and subsequent tumor development. Early-stage detection of cancer cells results in a remarkable 99% survival rate. This research presents a microwave imaging technique for the non-invasive identification of tumors in the initial stages within the women's breast.
View Article and Find Full Text PDFWith the rapid development of terahertz-enabled devices, the study of miniaturized and integrated systems has attracted significant attention. We experimentally demonstrate an imaging-based pixelated metamaterial for detecting terahertz molecular fingerprints related to intermolecular vibrations and large-amplitude intramolecular modes, including chemical identification and compositional analysis. The compact THz sensor consists of a 4 × 4 pixelated filter-detector array with transmission resonances tuned to discrete frequencies.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!