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Abnormal dynamic features of cortical microstates for detecting early-stage Parkinson's disease by resting-state electroencephalography: Systematic analysis of the influence of eye condition.
Heliyon
January 2025
Centro de Investigación e Innovación en Bioingeniería, Universitat Politècnica de València, 46022, València, Spain.
Resting state electroencephalography (EEG) has proved useful in studying electrophysiological changes in neurodegenerative diseases. In many neuropathologies, microstate analysis of the eyes-closed (EC) scalp EEG is a robust and highly reproducible technique for assessing topological changes with high temporal resolution. However, scalp EEG microstate maps tend to underestimate the non-occipital or non-alpha-band networks, which can also be used to detect neuropathological changes.
View Article and Find Full Text PDFOral cannabidiol did not impair learning and memory in healthy adults.
J Cannabis Res
January 2025
Department of Biology, Colorado State University Pueblo, 2200 Bonforte Blvd, Pueblo, CO, 81001, USA.
Background: The effect of oral Cannabidiol (CBD) on interference during learning and memory (L&M) in healthy human volunteers has not been studied.
Method: A two-arm crossover, randomized, double-blind, placebo-controlled trial was conducted at Colorado State University Pueblo (CSU Pueblo) to evaluate the effects of 246 mg oral CBD on L&M in healthy adults. Among 57 healthy volunteers enrolled, 35 were included in the analyses.
Minimally important change on the Columbia Impairment Scale and Strengths and Difficulties Questionnaire in youths seeking mental healthcare.
BMJ Ment Health
January 2025
Cundill Centre for Child and Youth Depression, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
Background: Evidence-based mental health requires patient-relevant outcome data, but many indicators lack clinical meaning and fail to consider youth perceptions. The minimally important change (MIC) indicator designates change as meaningful to patients, yet is rarely reported in youth mental health trials.
Objective: This study aimed to establish MIC thresholds for two patient-reported outcome measures (PROMs), the Columbia Impairment Scale (CIS) and the Strengths and Difficulties Questionnaire (SDQ), using different estimation methods.
Prefrontal working memory activity slots support sequence memory similar to hippocampal long-term memory position recall.
Neuron
January 2025
Neuropsychology and Cognitive Neuroscience Unit, Department of Psychology, University of Zurich, Zurich, Switzerland; Neuroscience Center Zurich, University of Zurich, Zurich, Switzerland. Electronic address:
Prefrontal cortex and medial temporal lobe information processing might not be that different after all. In this issue of Neuron, Whittington et al. show that prefrontal cortex working memory slot activity enables sequence memorizing similar to hippocampal long-term memory.
View Article and Find Full Text PDFMoral injury in treatment-seeking police officers: A qualitative study.
Psychol Trauma
January 2025
ARQ Centrum'45, ARQ National Psychotrauma Centre.
Objective: In their work, police officers are routinely exposed to potentially traumatic events, some of which may also be morally distressing. Moral injury refers to the multidimensional impact of exposure to such potentially morally injurious events (PMIEs). Mainly originating from a military context, there is little empirical research on moral injury in policing.
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