Considering that there are many alternatives in the literature for composing groups in collaborative learning contexts, we present a proposal that exhibits several features. First, and from the operational point of view, our proposal is highly flexible because i) it allows for several group sizes and an arbitrary array of grouping attributes, and ii) it may be easily adapted to consider several homogeneity/heterogeneity criteria. Second, and from the algorithmic point of view, it combines the best of two apparently opposite worlds: it uses a local brute-force search within an iterative process guided by a randomized heuristic criterion. Thus, this approach is still Non-Polynomic (NP) but in terms of the size of the groups, whereas is Polynomic (P) in terms of the number of students. Third, the experiments with several datasets, with student numbers varying from 20 to 3500, demonstrate reasonable performance and running times for this approach. We contrasted these times with those reported in 19 related works and, first taking into account certain considerations, we found that ours were lower in most cases. Nevertheless, and as the fourth feature, we make available both the datasets and the source code to allow for more objective comparisons of approaches, including our own.
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http://dx.doi.org/10.1016/j.heliyon.2021.e07249 | DOI Listing |
Methods Cell Biol
January 2025
Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada; Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada; Arnie Charbonneau Cancer Research Institute, Calgary, AB, Canada. Electronic address:
Breast cancer is the most common cancer in women and continues to have a significant impact in cancer-associated deaths worldwide. Investigating the complex roles of infiltrating immune subsets within the tumor microenvironment (TME) will enable a better understanding of disease progression and reveal novel therapeutic strategies for patients with breast cancer. The mammary-specific expression of polyomavirus middle T oncoprotein (MMTV-PyMT) was first established in 1992 by William Muller and is the most commonly used genetically engineered mouse model (GEMM) for breast cancer research.
View Article and Find Full Text PDFJ Oral Maxillofac Surg
January 2025
Undergraduate Dentistry Student, Research Committee, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Background: Operative treatment of advanced mandibular tumors may require excision of a portion of the mandible including the condyle. It is not clear how condylar excision affects postoperative quality of life (QoL).
Purpose: The study purpose was to measure the association between operative management of the condyle and postoperative health-related QoL and temporomandibular joint (TMJ) function.
Int J Biol Macromol
January 2025
College of Biotechnology, Tianjin University of Science and Technology, Tianjin 300457, China; Key Laboratory of Industrial Fermentation Microbiology, Ministry of Education and Tianjin, Tianjin 300457, China. Electronic address:
Probiotics intervention by Lactobacillus acidophilus has potential effect on alleviating obesity and insulin resistance. However, the limited knowledge of functional substances and potential regulatory mechanisms hinder their widespread application. Herein, L.
View Article and Find Full Text PDFHum Immunol
January 2025
The Second Affiliated Hospital of Guangxi Medical University, Department of Nephrology, Nanning, Guangxi 530021, China. Electronic address:
Background: Microscopic polyangiitis (MPA) is a severe multisystem autoimmune disease featured by small-vessel vasculitis with few or no immune complex, also has a significant genetic predisposition. Growing evidence has confirmed that STAT4 gene is tightly associated with multiple autoimmune diseases, but its contribution to MPA onset is still elusive.
Objective: The aim was to investigated the association between STAT4 gene polymorphisms (rs7572482, rs7574865 and rs12991409) and MPA susceptibility in a Guangxi population of China.
J Liposome Res
January 2025
SiteDel Group, Department of Pharmacy, University of Oslo, Blindern, Oslo, Norway.
In this study, liposomes consisting of soybean phosphatidyl choline (SoyPC) and different molar concentrations (10 mol% and 20 mol%) of dioleoyl trimethylammoniumpropane (DOTAP) were prepared by the thin film hydration method and coated with sodium hyaluronate (NaHA) of different MWs (8-15 kDa, 30-50 kDa and 90-130 kDa) and concentrations (0.01-0.2% w/w) using phosphate buffer (PB) or glycerol phosphate buffer (G-PB) as the hydration medium.
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