A nonimmunocompromised patient developed life-threatening soft tissue infection with , , and that progressed despite maximum antifungal therapies and aggressive debridement. Interleukin-7 immunotherapy resulted in clinical improvement, fungal clearance, reversal of lymphopenia, and improved T-cell function. Immunoadjuvant therapies to boost host immunity may be efficacious in life-threatening fungal infections.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231366 | PMC |
http://dx.doi.org/10.1093/ofid/ofab256 | DOI Listing |
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