Background: Although group (SAG) endocarditis is considered a severe disease associated with abscess formation and embolic events, there is limited evidence to support this assumption.
Methods: We performed a retrospective analysis of prospectively collected data from consecutive patients with definite SAG endocarditis in 28 centers in Spain and Italy. A comparison between cases due to SAG endocarditis and viridans group streptococci (VGS) or group (SGG) was performed in a 1:2 matched analysis.
Results: Of 5336 consecutive cases of definite endocarditis, 72 (1.4%) were due to SAG and matched with 144 cases due to VGS/SGG. SAG endocarditis was community acquired in 64 (88.9%) cases and affected aortic native valve in 29 (40.3%). When comparing SAG and VGS/SGG endocarditis, no significant differences were found in septic shock (8.3% vs 3.5%, = .116); valve disorder, including perforation (22.2% vs 18.1%, = .584), pseudoaneurysm (16.7% vs 8.3%, = .108), or prosthesis dehiscence (1.4% vs 6.3%, = .170); paravalvular complications, including abscess (25% vs 18.8%, = .264) and intracardiac fistula (5.6% vs 3.5%, = .485); heart failure (34.7% vs 38.9%, = .655); or embolic events (41.7% vs 32.6%, = .248). Indications for surgery (70.8% vs 70.8%; = 1) and mortality (13.9% vs 16.7%; = .741) were similar between groups.
Conclusions: SAG endocarditis is an infrequent but serious condition that presents a prognosis similar to that of VGS/SGG.
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| http://dx.doi.org/10.1093/ofid/ofab163 | DOI Listing |
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