AI Article Synopsis
- Bacteremia has a known link to colorectal cancers, particularly due to the survival of a specific bacterium in the acidic environment of tumors.
- A patient exhibited symptoms like fever and abdominal pain; imaging revealed colonic tumors and a potential brain metastasis.
- The patient underwent surgery for tumor removal, and blood tests confirmed the presence of the bacterium, raising concerns about its role in sepsis.
Article Abstract
There is a known relationship between bacteremia and colorectal malignancies. is a gram-positive, anaerobic, spore-forming bacterium that can survive the acidic colorectal tumor microenvironment, where it is thought to enter the blood by tumor-mediated epithelial tissue damage. While in circulation, can release exotoxins which may lead to life-threatening sepsis. The patient in this case presented with a mild fever, abdominal pain, and left hand weakness. Imaging of the head and abdomen revealed a right frontal lucency and wall thickening of the ascending colon. Two colonic adenocarcinomas were found and removed via an exploratory laparotomy and right hemicolectomy. The blood culture was positive for . Brain MRI confirmed a right frontal mass concerning for metastasis. Here, we discuss the relationship between colonic cancers and bacteremia.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220233 | PMC |
| http://dx.doi.org/10.1016/j.idcr.2021.e01189 | DOI Listing |
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