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SARS-CoV-2 Evolution: Implications for Diagnosis, Treatment, Vaccine Effectiveness and Development.
Vaccines (Basel)
December 2024
Microbiology and Virology Unit, Department of Biomedical Sciences, University of Cagliari, University Campus, 09042 Monserrato, Italy.
The COVID-19 pandemic, driven by the rapid evolution of the SARS-CoV-2 virus, presents ongoing challenges to global public health. SARS-CoV-2 is characterized by rapidly evolving mutations, especially in (but not limited to) the spike protein, complicating predictions about its evolutionary trajectory. These mutations have significantly affected transmissibility, immune evasion, and vaccine efficacy, leading to multiple pandemic waves with over half a billion cases and seven million deaths globally.
View Article and Find Full Text PDFAssociations of Pregnancy Timing Relative to the COVID-19 Pandemic, Maternal SARS-CoV-2 Infection, and Adverse Perinatal Outcomes.
Ann Epidemiol
January 2025
South Carolina SmartState Center for Healthcare Quality, South Carolina, USA; Department of Health Promotion, Education and Behavior, University of South Carolina Arnold School of Public Health, Institution address: 915 Greene Street, Columbia, SC 29208, USA. Electronic address:
Purpose: To examine associations between COVID-19 pandemic and maternal SARS-CoV-2 infection with perinatal outcomes.
Methods: We conducted a retrospective cohort study of 189,097 singleton births in South Carolina (2018-2021). Pregnancy timing relative to the pandemic was classified as pre-pandemic (delivered before March 1, 2020), partial pandemic overlap (conceived before and delivered during the pandemic), or pandemic (conceived and delivered during the pandemic).
Uptake of Recommended Vaccines During Pregnancy Among Publicly and Privately Insured People in the United States, December 2020-September 2022.
Am J Public Health
January 2025
Stacey L. Rowe is with the School of Nursing and Health Professions, University of San Francisco, San Francisco, CA. Sheena G. Sullivan is with the School of Clinical Sciences, Monash University, Melbourne, Australia. Flor M. Munoz is with the Department of Pediatrics, Baylor College of Medicine, Houston, TX. Matthew M. Coates and Onyebuchi A. Arah are with the Department of Epidemiology, Fielding School of Public Health, University of California, Los Angeles. Annette K. Regan is with the Department of Research and Evaluation, Kaiser Permanente Research, Pasadena, CA.
To estimate maternal COVID-19, influenza, and pertussis vaccine uptake during pregnancy by insurance type and identify factors characterizing those vaccinated and unvaccinated. We conducted a US cohort study of pregnant individuals (for pregnancies ending December 11, 2020-September 30, 2022) using insurance claims data. We calculated vaccination probability using Kaplan-Meier methods and identified factors associated with vaccination through binomial regression with inverse probability weights.
View Article and Find Full Text PDFThe contribution of self-compassion and social support to women's mental health during pregnancy: A comparison between international and national crisis periods.
Psychol Trauma
January 2025
Louis and Gabi Weisfeld School of Social Work, Bar-Ilan University.
Objective: The present study aimed to examine the contribution of self-compassion and perceived social support from family, partner, and friends, along with pregnancy-related variables, and concerns about the fetus and childbirth, to pregnant women's mental health, comparing two different crises.
Method: A sample of 220 women was recruited during the COVID-19 pandemic, and another sample of 224 women was recruited during the Israel-Hamas war. Participants were enrolled through a convenience sample and completed a set of self-report questionnaires.
While maternal mortality decreased during the Millennium Development Goals era, it remains unacceptably high, with stagnation in reductions possible due to shocks such as COVID-19. Most women in low- and middle-income countries already receive antenatal care and over half give birth in health facilities. In cities, use of health facilities for childbirth is near universal (>90%).
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