Modern computational intelligence based drug repurposing for diabetes epidemic.

Diabetes Metab Syndr

School of Electronics Engineering, KIIT University, Bhubaneswar, Odisha, India. Electronic address:

Published: December 2021

Background And Aim: Objectives are to explore recent advances in discovery of new antidiabetic agents using repurposing strategies and to discuss modern technologies used for drug repurposing highlighting diabetic specific web portal.

Methods: Recent literature were studied and analyzed from various sources such as Scopus, PubMed, and IEEE Xplore databases.

Results: Drugs like Niclosamideethanolamine, Methazolamide, Diacerein, Berberine, Clobetasol, etc. with possibility of repurposing to curb diabetes can be potential late-stage clinical candidates, providing access to information on pharmacology, formulation, and probable toxicity if any.

Conclusions: With collaboration of artificial intelligence (AI) with pharmacology, the efficiency of drug repurposing can improve significantly.

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http://dx.doi.org/10.1016/j.dsx.2021.06.017DOI Listing

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