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Lithium Intoxication After Sleeve Gastrectomy: A Case Report and Differential Diagnosis.
Noro Psikiyatr Ars
November 2024
Department of Psychiatry, Bezmiâlem Vakıf University Faculty of Medicine, Istanbul, Türkiye.
Bariatric surgery rates have been increasing in the treatment of obesity worldwide recently. In addition to many physical changes after bariatric surgery, the bioavailability of medications can also be significantly affected. In this article, we present a 51-year-old female patient diagnosed with lithium toxicity after sleeve gastrectomy surgery.
View Article and Find Full Text PDFEarly diagnosis of nonconvulsive status epilepticus due to lithium intoxication using 6-channel electroencephalography.
CJEM
December 2024
Department of Forensic Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima City, Hiroshima, 734-8553, Japan.
Introduction: Nonconvulsive status epilepticus is a severe complication of lithium intoxication that requires prompt diagnosis and treatment. While conventional electroencephalography (EEG) remains the gold standard for diagnosis for nonconvulsive status epilepticus, its implementation in emergency settings can be challenging and time-consuming. We present a case in which simplified EEG with six electrodes enabled rapid detection and monitoring of nonconvulsive status epilepticus in lithium intoxication in the emergency setting.
View Article and Find Full Text PDFBackground: Despite a variability in response and a narrow therapeutic index, Lithium (Li) remains the gold standard treatment for bipolar disorders (BD), and a treatment of choice for unipolar disorders (UD). Red blood cell Li concentration (RBCLiC) and red blood cell/plasma Li ratio (LiR) have been studied in many areas of mood disorders (such as acute or chronic Li efficacy, adherence, side effects (SE), intoxication management) as well as in several research domains. This systematic review aims to synthesize the existing literature.
View Article and Find Full Text PDF[Intoxications with trace metal elements: A new concept of the metal profile].
Ann Biol Clin (Paris)
August 2024
Laboratoire de Pharmacologie-Toxicologie, Faculté de Médecine et de Pharmacie, Université Mohamed V de Rabat, 10001 Rabat, Maroc.
Article Synopsis
- * TMEs are categorized into essential elements (like iron and zinc) necessary for bodily functions and toxic elements (like mercury and lead) that are harmful and have no physiological role, with potential for illness stemming from both categories at high concentrations.
- * Techniques like Inductively Coupled Plasma Mass Spectrometry (ICP-MS) enhance detection and quantification of TMEs in biological samples, aiding in the diagnosis and management of TME intoxications through a novel approach known as the metal profile.
Lithium may cause toxicity as it has a narrow therapeutic range. Lithium intoxication may manifest in the form of acute, acute on chronic and chronic intoxication. Neurotoxicity is a common component of chronic lithium intoxication and the symptoms include tremor, ataxia, dysarthria, extrapyramidal symptoms, hyperreflexia, seizures and status epilepticus.
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