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Background: Snakebite is a neglected tropical disease that causes significant morbidity and mortality in India. In this study, we describe the clinical characteristics and outcomes of Echis carinatus sochureki envenoming from Western Rajasthan. We document the clinical ineffectiveness of the currently available Indian polyvalent antivenom in managing E.

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Detection of enoxaparin and argatroban by use of the novel viscoelastic coagulometer ClotPro.

Sci Rep

November 2024

Department of Anaesthesia, Intensive Care Medicine and Pain Medicine, Division of General Anaesthesia and Intensive Care Medicine, Medical University of Vienna, Währinger Gürtel 18-20, Wien, Vienna, 1090, Austria.

Article Synopsis
  • The study investigates point-of-care diagnostic tests for monitoring the anticoagulants enoxaparin and argatroban in critically ill patients who face risks of thrombosis and bleeding.
  • Blood samples from twelve healthy volunteers were used to evaluate the performance of the ClotPro viscoelastic coagulometer alongside traditional coagulation tests.
  • Results indicated that the RVV test for enoxaparin is not reliable, while the ECA test shows strong correlation and may be a better option for accurately detecting argatroban levels.
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Article Synopsis
  • The observational study involved 52 patients, primarily male with a median age of 29, highlighting common envenomations, persistent symptoms, and treatments provided, including compression and physical therapy.
  • Key findings indicated that 61.5% of patients had persistent edema, with the clinic effectively addressing significant post-discharge issues through comprehensive wound care and referrals.
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Green pit viper (Peltopelor trigonocephalus) is a medically important endemic snake in Sri Lanka. Its envenoming commonly causes local effects such as pain, swelling, blistering, and lymphadenopathy and rarely causes venom-induced consumption coagulopathy as a systemic effect. Despite its frequent encounters in estates, commonly tea and cinnamon plantations, reports of envenoming are rare and limited to nine reports in the literature.

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